
Group Director
Minoru Yoshida, Ph.D.
Welcome to Chemical Genomics Research Group!
Chemical biology using chemistry as leverage has unraveled complex biological functions and has contributed much to the discovery of novel phenomena and their underlying mechanisms. Thanks to the recent technical advances, chemical biology has been able to develop more comprehensive approach to "Chemical Genomics". This project focuses on the development of a variety of original assay systems using newly identified genes, proteins and cell lines, and on the discovery of unique compounds (molecular ligands) that target specific biological molecules. Based on the activity of such novel molecular ligands, our effort will then be directed toward the identification of their target molecules and the elucidation of the role of their biological functions. Our goal is to deeply understand the biological systems and to construct the bases of drug discovery.
Research Subjects
1. Construction of unique assay systems and screening for molecular ligands
2. Design and synthesis of novel of molecular ligands and development of labeled probes
3. Target identification of molecular ligands
4. Mode of action of molecular ligands and its application to life sciences
Press Release
6/14/2010
New research uncovers elusive target of antifungal agent (Molecular Ligand Target Team)
News
7/11/2011
2011 RIKEN Chemical Biology Symposium will be held on October 20-21.
March, 2011
Dr. Yoshida (Group Director) won the Japan Society for Bioscience, Biotechnology, and Agrochemistry Award.









