Careers

Seeking a Research Scientist, Postdoctoral Researcher, Research Associate, Technical Scientist or Technical Staff(IMS103-1801)

Research field

The mission of our laboratory is to understand the origins and functions of non-coding transcription in human genome, with a focus on long non-coding RNAs and enhancer RNAs implicated in diseases. We have been at the forefront of annotating these non-coding RNAs using large-scale in-house transcriptomic datasets (e.g. FANTOM). We also integrate our in-house datasets with public epigenomic and genetic datasets to gain insights into the roles of non-coding RNAs in human diseases. Our team is primarily composed of bioinformatic analysts specialized in transcriptomics and genetics, but we are working closely with experimental biologists of other teams on technology development (e.g. single-cell transcriptomics) as well as other collaborative projects.

About the Laboratory for Genome Information Analysis:
Laboratory for Genome Information Analysis Website

About the Center for Integrative Medical Sciences:
Center for Integrative Medical Sciences Website

Relevant publications:
Hon CC et al, An atlas of human long non-coding RNAs with accurate 5’ ends. Nature (2017)
de Rie D et al, The FANTOM5 integrated expression atlas of miRNAs and their promoters. Nature Biotechnology (2017)
Hon CC et al, The Human Cell Atlas: Technical approaches and challenges. Briefings in Functional Genomics (2017)

Job title and description

Position available

One opening for Research Scientist, Postdoctoral Researcher, Research Associate, Technical Scientist or Technical Staff in bioinformatics

Job description

Project Name:

"Identification of functional RNAs implicated in central nervous system diseases and their functional analyses"
「中枢疾患におけるfunctional RNAの同定とその機能解析」(in Japanese)

The successful candidate will integrate public and proprietary datasets of transcriptomics (e.g. RNA-Seq, CAGE), epigenomics (e.g. Hi-C, ATAC-Seq) and genetics (GWAS and eQTL) to prioritize non-coding RNAs relevant to neurological disorders. Single-cell transcriptome profiling of cellular disease models will be used to identify the molecular signatures of the cell-types relevant to neurological disorders. The candidate will integrate public epigenomic and genetic datasets with these disease relevant molecular signatures to nominate non-coding RNAs for genetic perturbations (e.g. CRISPR interference). The disease relevance of these non-coding RNAs will be evaluated by integrative analyses of the datasets generated from cellular phenotypic assays and transcriptomic profiling after genetic perturbation. The ultimate goal is to identify disease-relevant functional non-coding RNAs with therapeutic potentials. The candidate is expected to tightly collaborate with other experimental researchers in the division.

The difference in positions is as follows:

  • Research Scientist: Carries out research and other work in accordance with laboratory research themes.
  • Postdoctoral Researcher: Carries out research and other work in accordance with laboratory research themes under the mentorship and training of supervisors.
  • Research Associate: Carries out research and other work in accordance with laboratory research themes under the direction of supervisors.
  • Technical Scientist: Develops and enhances the needed technologies for laboratory research themes under the direction of supervisors.
  • Technical Staff: Provides technical support for laboratory research themes.

Qualifications

Common to all positions

  1. Should have an experience and knowledge in bioinformatics.
  2. Should have solid programming skills (Perl, Python and/or R) and acquaintance with Unix/Linux.
  3. Should be familiar with genomics technologies, in particular those relevant to applications to next generation sequencing (e.g. RNA-seq, ChIP-seq, CAGE, etc.).
  4. Should have an experience and knowledge in analyses of next-generation sequencing transcriptomic and epigenomic datasets.
  5. Should have deep interests in functions and origins of non-coding RNAs.
  6. General knowledge of experimental biology and functional genomics (e.g. CRISPR interference) is desired.
  7. Additional experience and knowledge in genetics (e.g. GWAS and eQTL) of common diseases, single-cell transcriptomics and gene regulatory networks are meritorious, but not required.
  8. Should be highly motivated with competence in completing tasks independently.
  9. Should have excellent communication skills and be able to engage in research in a coordinated manner in order to complete the assigned tasks with the members of mixed nationalities.
  10. Comfortable with English as a professional language for scientific discussion and publication (Japanese language skills are NOT required).

Research Scientist, Postdoctoral Researcher

PhD holder in fields indicated under [Job description]. Candidates with less than three years postdoctoral experience will be considered for the position of Postdoctoral Researcher.

Research Associate

Master's degree holder in fields indicated under [Job description] or equivalent abilities. Should also have a strong desire to earn a PhD and motivation to advance to a higher position.

Technical Scientist

Holder of BA degree or above with substantial expertise and skills relevant to the fields indicated under [Job description]. Or equivalent abilities and more than five years experience in relevant fields.

Technical Staff

Graduate of a professional training school, junior college, university or graduate school with expertise and skills relevant to fields indicated under [Job description]. Or equivalent abilities and more than two years experience in relevant fields.

Work location

RIKEN Center for Integrative Medical Sciences
1-7-22 Suehiro-cho, Tsurumi-ku, Yokohama, Kanagawa 230-0045, Japan

Salary and benefits

Terms of contract

  1. A one-year fixed-term employment contract, renewable based on evaluation, to a maximum of February 28, 2021, the end date of the project.
  2. RIKEN may adjust the above maximum period of renewability based on a) the employee’s abilities, work load at the time of contract completion, performance and work attitude and b) the continuation of the employee’s center, laboratory or project and RIKEN’s management situation and budget at the time. In principle, employment contracts will not be renewed for individuals older than 65 years.
  3. The employee’s period of fixed-term employment cannot exceed 10 years from the initial date of hire (or 10 years from April 1, 2013 for fixed-term employees already at RIKEN prior to this date).

Salary

Salary is determined annually on the basis of the employee’s experience, abilities and performance. Commuting and housing allowances will be provided in accordance with RIKEN regulations and social insurance applies (health insurance, pension insurance, worker’s accident compensation insurance, unemployment insurance, etc.).
Mandatory membership in the RIKEN Mutual Benefit Society (RIKEN Kyosaikai).

Holidays

Saturdays and Sundays, Japanese national holidays, New Year holidays (Dec.29-Jan.3), and RIKEN Foundation Day (4th Monday in October).

Other provisions

- Other provisions are in accordance with RIKEN regulations.
- RIKEN’s Gender Equity Program promotes various measures to create a workplace where both men and women can give full rein to their talents and abilities. When applicants are judged to be equally qualified on the basis of fair and impartial criteria, women applicants will be given preference.
- Research Scientist, Postdoctoral Researcher and Research Associate are eligible for an exemption from repayment of category 1 JASSO scholarship loans if they were enrolled in the program before fiscal year 2003.

Required documents and deadlines

Prepare the documents below as PDF files and send them to IMS-jobs[at]ml.riken.jp (replace “[at]” with ”@”).
*Write“Application Documents; [IMS103-1801] IMS_your desired position (e.g. Research Scientist)” in the subject line.

Documents to submit

Research Scientist, Postdoctoral Researcher, Research Associate:

  1. CV WORD(56KB) or EXCEL(58KB) with photograph and e-mail address (Please indicate the desired position (e.g. Research Scientist) and the open call ID [IMS103-1801] in the upper right corner of the CV.)
    *Using the RIKEN format above is appreciated.
  2. List of publications (articles, reviews and books), presentations, etc. in past 5 years.
  3. Brief description of previous research and achievements, and future research plans (within two A4-size pages).
  4. Recommendation Letter (1)
    • The signature (or seal) of the person providing the recommendation is required. In the case of scanned or digital signature or an email letter of recommendation, please be sure to include contact information.
    • If it is difficult to obtain a recommendation letter from the current supervisor, a recommendation from a third party will be accepted. The letter of recommendation should be addressed to the “Director of the Center for Integrative Medical Sciences.”
    • If the person providing the recommendation will send the letter directly, please send it to the address indicated in [Contact Information] below.
  5. PhD/Master degree diploma
    • This document can be sent anytime up until the day of final interview.
  6. List of competitive external funds obtained (e.g. Grants-in-Aid for Scientific Research [Kakenhi]; indicate whether you are the representative researcher or the collaborator)

Technical Scientist, Technical Staff:

  1. CV WORD(56KB) or EXCEL(58KB) with photograph and e-mail address (Please indicate the open call ID [IMS103-1801] and the desired position (e.g. Technical Scientist) in the upper right corner of the CV.)
    *Using the RIKEN format above is appreciated.
  2. Statement of Purpose and brief description of future aspirations (within one A4-size page).
  3. List of skills and experience (within one A4-size page).
  4. Recommendation Letter (1)
    • The signature (or seal) of the person providing the recommendation is required. In the case of scanned or digital signatures and email letters of recommendation, please be sure to include contact information.
    • If it is difficult to obtain a recommendation letter from the current supervisor, a recommendation from a third party will be accepted. The letter of recommendation should be addressed to the “Director of the Center for Integrative Medical Sciences.”
    • If the person providing the recommendation will send the letter directly, please send it to the address indicated in [Contact Information] below.
  5. Diploma
    • This document can be sent anytime up until the day of final interview.

*Note: Application documents will not be returned.

Deadline

Until the position is filled

Handling of personal data

Submitted documents are strictly protected under the RIKEN Privacy Policy and used only for the purpose of applicant screening and hiring. Personal information will not be disclosed, transferred or loaned to a third party under any circumstances.

Selection process

Only persons who pass the application screening will be interviewed.

Start of employment

Earliest date possible (negotiable)

Contact information

Any questions about this position should be sent to the email address given below.
Please write "Open call (IMS103-1801) Laboratory for Genome Information Analysis, IMS" in the subject line.

For application documents and general questions:

Recruiting staff for RIKEN Center for Integrative Medical Sciences
Administrative Division, RIKEN Yokohama Branch
IMS-jobs[at]ml.riken.jp (replace “[at]” with ”@”)

For research contents:

Laboratory for Genome Information Analysis
Team Leader: Chung-Chau HON (Ph.D)
chungchau.hon[at]riken.jp
(replace “[at]” with ”@”)