Centers & Labs

RIKEN Brain Science Institute

Laboratory for Integrated Theoretical Neuroscience

Laboratory Head: Hiroyuki Nakahara (Ph.D.)
Hiroyuki  Nakahara(Ph.D.)

The long-term goal of our laboratory is to understand the computational principles that underlie the way neural systems realize adaptive behavior, decision-making, and associated learning. In particular, we focus on (1) reward-based learning and decision-making and (2) social learning and decision-making. Toward this goal, we address computational questions by building computational and mathematical models. We also use human fMRI in combination with quantitative approaches such as model-based analysis and neural decoding techniques. We further develop quantitative techniques and methods for realizing innovative data analysis in neuroscience, and also theories and models for brain-based artificial intelligence. In collaborative work with experimental investigators, we investigate the topics of our interest, using various types of experimental data.

Main Research Field

Complex systems

Related Research Fields

Informatics / Social sciences / Interdisciplinary science and engineering / Mathematical and physical sciences / Biological Sciences / Medicine, dentistry, and pharmacy

Keywords

  • Decision-making
  • Learning theory, Information geometry
  • Reinforcement learning
  • Social intelligence
  • Neural computation

Selected Publications

  1. Terada S, Sakurai Y, Nakahara H, Fujisawa S.:
    "Temporal and rate coding for discrete event sequences in the hippocampus."
    Neuron, 94, 1248-1262 (2017)
  2. Nakahara, H.:
    "Multiplexing signals in reinforcement learning with internal models and dopamine."
    Curr Opin Neurobiol, 25, 123-129 (2014)
  3. Suzuki, S., Harasawa, N., Ueno, K., Gardner, JL., Ichinohe, N., Haruno, M., Cheng, K., and Nakahara, H.:
    "Learning to simulate others' decisions."
    Neuron, 74(6), 1125-1137 (2012)
  4. Bromberg-Martin, ES., Matsumoto, M., Nakahara, H., and Hikosaka, O.:
    "Multiple timescales of memory in lateral habenula and dopamine neurons."
    Neuron, 67(3), 499-510 (2010)
  5. Nakahara, H., and Kaveri, S.:
    "Internal-Time Temporal Difference Model for Neural Value-based Decision Making.", Neural Comput, 22(12), 3062-3106 (2010)
  6. Santos, GS., Gireesh, ED., Plenz, D., and Nakahara, H.:
    "Hierarchical interaction structre of neural activities in cortical slice cultures."
    J Neurosci, 30(26), 8720-8733 (2010)
  7. Nakahara, H., Amari, S., and Richmond, BJ.:
    "A comparison of descriptive models of a single spike train by information-geometric measure."
    Neural Comput, 18(3), 545-568 (2006)
  8. Nakahara, H., Itoh, H., Kawagoe, R., Takikawa, Y., Hikosaka, O.:
    "Dopamine neurons can represent context-dependent prediction error."
    Neuron, 41(2), 269-280 (2004)
  9. Nakahara, H., and Amari, S.:
    "Information geometric measure for neural spikes."
    Neural Comput, 14(10), 2269-2316 (2002)
  10. Nakahara, H., Doya, K., and Hikosaka, O.:
    "Parallel cortico-basal ganglia mechanisms for acquisition and execution of visuomotor sequences: A computational approach."
    J Cognitive Neurosci, 13(5), 626-647 (2001)

Lab Members

Principal Investigator

Hiroyuki Nakahara
Laboratory Head

Core Members

Ning MA
Scientist
Chong Chen
Research Scientist
Yasuhiro Mochizuki
Research Scientist
Norihiro Harasawa
Technical Staff I
Megumi Morii
Technical Staff II
Youqi Ye
Technical Staff II
Jingyan Sun
Technical Staff II

Contact information

2-1 Hirosawa, Wako, Saitama 351-0198, Japan

Email: hn-hp [at] brain.riken.jp

Related links

Recent research results