Centers & Labs

Chief Scientist Laboratories

Elements Chemistry Laboratory

Chief Scientist: Masanobu Uchiyama (D.Phar.)
Masanobu  Uchiyama(D.Phar.)

Research in our laboratory spans the traditional areas of organic, inorganic and physical chemistry as well as interdisciplinary areas of modern chemical research, focusing in particular on the chemistry of elements (elements chemistry). We aim to better understand the reactions, properties, and structures of chemical substances not only by means of experimental approaches based on synthetic organic chemistry and spectroscopy, but also from a theoretical viewpoint based on computational chemistry. Our research interests include development of innovative chemical reactions, and design and synthesis of new functional molecules.

Main Research Field


Research Subjects

  • Periodic table-traversing chemistry that transcends the frameworks of organic chemistry, inorganic chemistry, and metallic chemistry
  • Development of advanced molecular transformation methods supporting materials science and life sciences
  • Design and production of materials by utilizing computational chemistry

Selected Publications

  1. Otsuka, M., Takita, R., Kanazawa, J., Miyamoto, K., Muranaka, A., and Uchiyama, M.:
    “Conjugation between sigma- and pi-Aromaticity in 1-C-Arylated Monocarba-closo-dodecaborate Anions”
    J. Am. Chem. Soc. 137, 15082-15085 (2015).
  2. Wang, D.-Y., Wang, C., and Uchiyama, M.:
    “Stannyl-Lithium: A Facile and Efficient Synthesis Facilitating Further Applications”
    J. Am. Chem. Soc. 137, 10488-10491 (2015).
  3. Tanioka, M., Kamino, S., Muranaka, A., Ooyama, Y., Ota, H., Shirasaki, Y., Horigome, J., Ueda, M., Uchiyama, M., Sawada, D., and Enomoto, S.:
    “Reversible Near-Infrared/Blue Mechanofluorochromism of Aminobenzopyranoxanthene”
    J. Am. Chem. Soc. 137, 6436-6439 (2015).
  4. Minami, H., Saito, T., Wang, C., and Uchiyama, M.:
    “Organoaluminum-Mediated Directed Cross-Coupling Reaction”
    Angew. Chem. Int. Ed. 54, 4665-4668 (2015).
  5. Mizukoshi, Y., Mikami, K., and Uchiyama, M.:
    “Aryne Polymerization Enabling Straightforward Synthesis of Elusive Poly(ortho-arylene)s”
    J. Am. Chem. Soc. 137, 74-77 (2015).
  6. Toriumi, N., Muranaka, A., Kayahara, E., Yamago, S., and Uchiyama M.:
    “In-plane Aromaticity in Cycloparaphenylene Dications: A Magnetic Circular Dichroism and Theoretical Study”
    J. Am. Chem. Soc. 137, 82-85 (2015).
  7. Nagashima, Y., Hirano, K., Takita, R., and Uchiyama, M.:
    trans-Diborylation of Alkynes: pseudo-Intramolecular Strategy Utilizing Propargylic Alcohol Unit”
    J. Am. Chem. Soc. 136, 8532-8535 (2014).
  8. Toriumi, N., Muranaka, A., Hirano, K., Yoshida, K., Hashizume, D., and Uchiyama, M.:
    “18π Tautomeric Benziphthalocyanine: A Functional Near-IR Dye with Tunable Aromaticity”
    Angew. Chem. Int. Ed. 53, 7814-7818 (2014).
  9. Shoji, Y., Tanaka, N., Mikami, K., Uchiyama, M., and Fukushima, T.:
    “A Two-coordinate Boron Cation Featuring C–B(+)–C Bonding”
    Nature Chem. 6, 498-503 (2014).
  10. Kim, R. H., Kim, H. J., Bae, I., Hwang, S. K., Velusamy, D. B., Cho, S. M., Takaishi, K., Muto, T., Hashizume, D., Uchiyama, M., Andre, P., Mathevet, F., Heinrich, B., Aoyama, T., Kim, D.-E., Lee, H., Ribierre, J.-C., and Park, C.:
    “Non-volatile Organic Memory with Sub-millimetre Bending Radius”
    Nature Commun. 5, 3583 (2014).

Lab Members

Principal Investigator

Masanobu Uchiyama
Chief Scientist

Core Members

Tetsuya Aoyama
Senior Research Scientist
Atsuya Muranaka
Senior Research Scientist
Yoshinao Shirasaki
Student Trainee
Yu Kitazawa
Student Trainee
Yui Masumoto
Junior Research Associate
Takuya Uehara
Student Trainee

Contact information

2-1 Hirosawa, Wako, Saitama 351-0198, Japan

Email: uchi_yama [at]

Annual research report