Centers & Labs

RIKEN Center for Sustainable Resource Science

Gene Discovery Research Group

Group Director: Kazuo Shinozaki (D.Sci.)
Kazuo  Shinozaki(D.Sci.)

Our group is discovering plant genes of which functions are linked to quantitative improvements in plants and those with new functions for minimizing the effects of the environmental stresses to achieve maximum productivity. Other targets of research include not only genes that respond to environmental changes and stimuli and adaptation but also genes involved in photosynthesis and productions of useful metabolites. Our group explores key genes involved in improved productivity and abiotic stress tolerance based on genomics including transcriptome and metabolome analyses, and are analyzing regulatory factors and signaling factors involved in the control of gene expression in response to abiotic environmental stresses. We also explore genes involved in metabolic regulation for the improvement plant productivity.

Main Research Field

Plant & Animal Science

Related Research Fields

Biology & Biochemistry / Molecular Biology & Genetics / Agricultural Sciences

Research Subjects

  • Exploration and analysis of regulatory factors and signaling factors in environmental stress responses
  • Exploration and use of genes involved in plant productivity using a reverse genetic approach
  • Development of environmental stress resistance wheat and rice
  • Development of systematic phenotype analysis platform (phenome analysis) for functional analysis of mutated genes

Selected Publications

  1. Takasaki, H., Maruyama, K., Takahashi, F., Fujita, M., Yoshida, T., Nakashima, K., Myouga, F., Toyooka, K., Yamaguchi-Shinozaki, K. and Shinozaki, K.:
    "SNAC-As, stress-responsive NAC transcription factors, mediate ABA-inducible leaf senescence."
    Plant J, 84, 1114-1123 (2015)
  2. Miyaji, T.*, Kuromori, T.*, Takeuchi, Y., Yamaji, N., Yokosho, K., Shimazawa, A., Sugimoto, E., Omote, H., Ma, J. F., Shinozaki, K. and Moriyama, Y.:
    "AtPHT4;4 is a chloroplast-localized ascorbate transporter in Arabidopsis."
    Nature Commun, 6, 5928 (2015)(* equally contribution)
  3. Fujita, M. and Shinozaki, K.:
    "Identification of polyamine transporters in plants: paraquat transport provides crucial clues."
    Plant Cell Physiol, 55, 855-861 (2015)
  4. Umezawa, T., Sugiyama, N., Takahashi, F., Anderson, J. C., Ishihama, Y., Peck, S. C. and Shinozaki, K.:
    "Genetics and phosphoproteomics reveal a protein phosphorylation network in the abscisic acid signaling pathway in Arabidopsis thaliana."
    Sci Signal, 6, rs8 (2013)
  5. Behnam, B., Iuchi, S., Fujita, M., Fujita, Y., Takasaki, H., Osakabe, Y., Yamaguchi-Shinozaki, K., Kobayashi, M. and Shinozaki, K.:
    "Characterization of the promoter region of an Arabidopsis gene for 9-cis-epoxycarotenoid dioxygenase involved in dehydration-inducible transcription."
    DNA Res., 20, 315-324 (2013)
  6. Myouga, F., Akiyama, K., Tomonaga, Y., Kato, A., Sato, Y., Kobayashi, M., Nagata, N., Sakurai, T. and Shinozaki, K.:
    "The chloroplast function database II: a comprehensive collection of homozygous mutants and their phenotypic/genotypic traits for nuclear-encoded chloroplast proteins."
    Plant Cell Physiol., 54, e2 (2013)
  7. Fujita, M., Fujita, Y., Iuchi, S., Yamada, K., Kobayashi, Y., Urano, K., Kobayashi, M., Yamaguchi-Shinozaki, K. and Shinozaki, K.:
    "Natural variation in a polyamine transporter determines paraquat tolerance in Arabidopsis"
    Proc. Natl. Acad. Sci. U. S. A., 109, 6343-6347 (2012)
  8. Takahashi, F., Mizoguchi, T., Yoshida, R., Ichimura, K. and Shinozaki, K.:
    "Calmodulin-dependent activation of MAP kinase for ROS homeostasis in Arabidopsis."
    Mol. Cell, 41, 649-660 (2011)
  9. Urano, K., Kurihara, Y., Seki, K., and Shinozaki, K.:
    "Omics' analyses of regulatory networks in plant abiotic stress responses."
    Curr.Opin. Plant Biol., 13, 132-138 (2010)
  10. Kuromori, T., Miyaji, T., Yabuuchi, H., Shimizu, H., Sugimoto, E., Kamiya, A., Moriyama, Y., and Shinozaki, K.:
    "ABC transporter AtABCG25 is involved in abscisic acid transport and responses."
    Proc. Natl. Acad. Sci. USA, 109, 2361-2366 (2010)

Lab Members

Principal Investigator

Kazuo Shinozaki
Group Director

Core Members

Takeshi Nakano
Senior Research Scientist
Takashi Kuromori
Senior Research Scientist
Keiichi Mochida
Senior Research Scientist
Miki Fujita
Research Scientist
Fumiyoshi Myouga
Research Scientist
Fuminori Takahashi
Research Scientist
Kaoru Urano
Research Scientist
Ayumi Nakano
Research Scientist
June-Sik Kim
Special Postdoctoral Researcher
Tomoko Miyaji
Postdoctoral Researcher
Hikaru Sato
Postdoctoral Researcher
Yukiko Kamide
Technical Staff I
David Jonathan Gifford
Technical Staff I
Saho Mizukado
Technical Staff II
Eriko Sugimoto
Technical Staff II
Chihiro Ohashi
Technical Staff II
Saya Kikuchi
Technical Staff II

Contact information

1-7-22 Suehiro-cho, Tsurumi-ku,
Yokohama City, Kanagawa,
230-0045, Japan

3-1-1 Koyadai,
Tsukuba, Ibaraki,
305-0074 Japan

2-1 Hirosawa,
Wako, Saitama,
351-0198 Japan

Email: kazuo.shinozaki [at] riken.jp

Related links

Recent research results

May 1, 2015: RIKEN RESEARCH
Plants' control complex
February 20, 2015: RIKEN RESEARCH
Sun safety for plants
January 5, 2015: Press Release
How vitamin C helps plants beat the sun