Centers & Labs

RIKEN Center for Advanced Photonics

Cloud-Based Eye Disease Diagnosis Joint Research Team

Team Leader: Masahiro Akiba (D.Eng.)
Masahiro  Akiba(D.Eng.)

Cloud-based analysis system capable of automated analysis of eye disease is developing using multi-dimensional optical coherence tomography (OCT) images for screening purpose. Quantitative information such as layer thickness and structural parameter is extracted from OCT images and non-OCT diagnostic parameters are associated for data mining purpose. Cloud-based eye disease analytic system can be well suited for screening and telemedicine.

Main Research Field

Complex systems

Related Research Fields

Interdisciplinary science and engineering


  • Biomedical optical measurement
  • Optometry
  • Optical scattering
  • Optical Coherence Tomography

Selected Publications

Papers with an asterisk(*) are based on research conducted outside of RIKEN.
  1. *Tomofumi Tani; Young-Seok Song; Takafumi Yoshioka; Tsuneaki Omae; Akihiro Ishibazawa; Masahiro Akiba; Akitoshi Yoshida.:
    "Repeatability and Reproducibility of Retinal Blood Flow Measurement Using a Doppler Optical Coherence Tomography Flowmeter in Healthy Subjects "
    Invest Ophthalmol Vis Sci. 58, 2891-2898 (2017).
  2. *Jun Cheng, Dacheng Tao, Ying Quan, Wong DW, Cheung GC, Akiba M, Jiang Liu..:
    " Speckle Reduction in 3D Optical Coherence Tomography of Retina by A-Scan Reconstruction "
    IEEE Trans Med Imaging. 35, 2270-2279 (2016)
  3. *Takada N, Omodaka K, Kikawa T, Takagi A, Matsumoto A, Yokoyama Y, Shiga Y, Maruyama K, Takahashi H, Akiba M, Nakazawa T.:
    " OCT-Based Quantification and Classification of Optic Disc Structure in Glaucoma Patients "
    PLoS One. 11:e0160226 (2016)
  4. *Nagaoka T, Tani T, Song YS, Yoshioka T, Ishibazawa A, Nakabayashi S, Akiba M, Yoshida A.:
    "Evaluation of Retinal Circulation Using Segmental-Scanning Doppler Optical Coherence Tomography in Anesthetized Cats. "
    Invest Ophthalmol Vis Sci. 57: 2936-41. (2016)
  5. *Omodaka K, Horii T, Takahashi S, Kikawa T, Matsumoto A, Shiga Y, Maruyama K, Yuasa T, Akiba M, Nakazawa T.:
    "3D evaluation of the lamina cribrosa with swept-source optical coherence tomography in normal tension glaucoma"
    PLoS One. 10, e0122347, (2015)

Lab Members

Principal Investigator

Masahiro Akiba
Team Leader

Core Members

Hideo Yokota
Deputy Team Leader
Shin Yoshizawa
Senior Scientist
Satoko Takemoto
Research Scientist
Shigeki Kudo
Research Scientist
Masahiko Morita
Postdoctoral Researcher
Norio Yamashita
Postdoctoral Researcher
Masaomi Nishimura
Technical Staff I
Guangzhou An
Visiting Scientist