Centers & Labs

RIKEN Center for Advanced Photonics

Image Processing Research Team

Team Leader: Hideo Yokota (D.Eng.)
Hideo  Yokota(D.Eng.)

Our goal is to develop original RIKEN data processing technology and multidimensional measurement technology in order to contribute to understanding biological phenomena. We are especially contributing to the fields of mathematical biology, bio-medical simulations as well as medical diagnostic and treatment technology by researching and developing new data and image processing technologies and establishing new tools for quantification of biological phenomena, intended for researchers both inside and outside RIKEN.

Main Research Field

Computer Science

Related Research Fields

Engineering / Biology & Biochemistry / Clinical Medicine / Mathematics

Research Subjects

  • Development of image processing systems.
  • Construction of live cell model describing phenomenon of living cell.
  • Construction of instrumentation system for bio-research data creation.

Selected Publications

  1. T. Sera, H. Yokota, R. Himeno, and G. Tanaka:
    "Gas dispersion of oscillatory flow in expanding and contracting multi-branching airways"
    International Journal of Heat and Mass Transfer, Vol. 65, pp. 627–634, 2013.
  2. T. Ijiri, S. Yoshizawa, Y. Sato, M. Ito, and H. Yokota:
    "Bilateral Hermite Radial Basis Functions for Contour-based Volume Segmentation"
    Computer Graphics Forum (Proc. of EUROGRAPHICS’13), Vo. 32(2), pp. 123-132, 2013.
  3. S. Hihara, C.-G. Pack, K. Kaizu, T. Tani, T. Hanafusa, T. Nozaki, S. Takemoto, T. Yoshimi, H. Yokota, N. Imamoto, Y. Sako, M. Kinjo, K. Takahashi, T. Nagai, and K. Maeshima:
    "Local Nucleosome Dynamics Facilitate Chromatin Accessibility in Living Mammalian Cells"
    Cell Reports, Vol. 2(6), pp. 1645-1656, 2012.
  4. T. Sera, H. Yokota, K. Uesugi, and N. Yagi:
    "Airway distension during lung inflation in healthy and allergic-sensitised mice in vivo"
    Respir. Physiol. Neurobiol., Vol. 185(3), pp. 639-646, 2012.
  5. S. Yoshizawa, A. Belyaev, and H. Yokota:
    "Shape and Image Interrogation with Curvature Extremalities"
    Journal for Geometry and Graphics, Vol. 16, No. 1, pp. 81-95, 2012.
  6. K. Kominami, T. Nagai, T. Sawasaki, Y. Tsujimura, K. Yashima, Y. Sunaga, M. Tsuchimochi, J. Nishi-mura, K. Chiba, J. Nakabayashi, K. Koyamada, Y. Endo, H. Yokota, A. Miyawaki, N. Manabe, and K. Sakamaki:
    "In Vivo Imaging of Hierarchical Spatiotemporal Activation of Caspase-8 during Apoptosis"
    PLoS ONE, Vol. 7(11), e50218:1-18, 2012.
  7. Y. Okamura-Oho, K. Shimokawa, S. Takemoto, A. Hirakiyama, S. Nakamura, Y. Tsujimura, M. Nishimura, T. Kasukawa, K. Masumoto, I. Nikaido, Y. Shigeyoshi, H. Ueda, G. Song, J. Gee, R. Himeno, and H. Yokota:
    "Transcriptome tomography for brain analysis in the web-accessible anatomical space"
    PLOS ONE, Vol. 7(9), e45373:1-10, 2012.
  8. K. Kominami , J. Nakabayashi, T. Nagai, Y. Tsujimura, K. Chib, H. Kimur, A. Miyawaki, T. Sawasaki, H. Yokota, N. Manabe, and K. Sakamaki:
    "The molecular mechanism of apoptosis upon caspase-8 activation: Quantitative experimental validation of a mathematical model"
    Biochimica et Biophysica Acta, Vol. 1823(10), pp. 1825-1840, 2012.
  9. T. Ijiri, T. Ashihara, N. Umetani, T. Igarashi, R. Haraguchi, H. Yokota, and K. Nakazawa:
    "A Kinematic Approach for Efficient and Robust Simulation of the Cardiac Beating Motion"
    PLoS ONE, Vol. 7(5), pp. e36706:1-9, 2012
  10. K. Fujisaki, N. Yamashita, and H. Yokota:
    "An automated three-dimensional internal structure observation system based on high-speed serial sectioning of steel materials"
    Precision Engineering, Vo. 36(2), pp. 315-321, 2012.

Lab Members

Principal Investigator

Hideo Yokota
Team Leader

Core Members

Shin Yoshizawa
Senior Scientist
Satoko Takemoto
Research Scientist
Takehiro Tawara
Research Scientist
Masahiko Morita
Postdoctoral Researcher
Norio Yamashita
Postdoctoral Researcher
Toshiharu Mukai
Visiting Scientist
Takashi Ijiri
Visiting Scientist
Sakiko Nakamura
Technical Staff I
Yuki Tsujimura
Technical Staff I
Masaomi Nishimura
Technical Staff I

Contact information

2-1 Hirosawa, Wako, Saitama 351-0198, Japan

Email: brict [at]