Centers & Labs

RIKEN SPring-8 Center

Imaging Development Team

Team Leader: Makina Yabashi (D.Eng.)
Makina  Yabashi(D.Eng.)

Coherent x-ray diffraction imaging is a burgeoning field directed toward determining the 3D structure of noncrystalline specimens at atomic resolution. Currently we are working to develop 3D x-ray diffraction microscopy that will shine new light in nano- and bio-technology at the nanometer resolution. With the emergent x-ray free electron lasers, the coherent x-ray diffraction imaging technique expects to find its ultimate application in imaging single macromolecules at near atomic resolution.

Research Subjects

  • Resonant coherent x-ray diffraction imaging with elemental specificity
  • High resolution 3D imaging of biological specimens and nano-structures
  • High contrast coherent diffraction imaging with FELs

Selected Publications

  1. H. Jiang, C. Song,T. Ishikawa, J. Miao et al.:
    "Quantitative 3D imaging of whole, unstained cells by using X-ray diffraction microscopy"
    Proc. Natl. Acad. Sci. USA, 107, 11234 (2010)
  2. C. Song, H. Jiang, A. P. Mancuso, B. Amirbekian, L. Peng, R. Sun, S. S Shah, Z. H. Zhou, T. Ishikawa, and J. Miao:
    "Quantitative imaging of single, unstained viruses with coherent X-rays"
    Phys. Rev. Lett., 101, 158101 (2008)
  3. C. Song, R. Bergstrom, D. Ramunno-Johnson, H. Jiang, D. Paterson, M. D. de Jonge, I. McNulty, J. Lee, K. Wang, and J. Miao:
    "Nanoscale imaging of buried structures with elemental specificity using resonant x-ray diffraction microscopy"
    Phys. Rev. Lett., 100, 025504 (2008)
  4. R. L. Sandberg, C. Song, P. W. Wachulak, D. A. Raymondson, A. Paul, B. Amirbekian, E. Lee, A. E. Sakdinawat, M. C. Marconi, C. S. Menoni, M. M. Murnane, J. J. Rocca, H. C. Kapteyn, and J. Miao:
    "High numerical aperture tabletop soft x-ray diffraction microscopy with 70 nm resolution"
    Proc. Natl. Acad. Sci. USA, 105, 24 (2008)
  5. C. Song, D. Ramunno-Johnson, Y. Nishino, Y. Kohmura, C.-C. Chen, T.-K. Lee, T. Ishikawa, and J. Miao:
    "Phase retrieval from exactly oversampled diffraction intensity through deconvolution"
    Phys. Rev. B, 75, 0120102 (2007)
  6. R. L. Sandberg, A. Paul, D. A. Raymondson, S. Hadrich, D. M. Gaudiosi, J. Holtsnider, R. I. Tobey, O. Cohen, M. Murnane, H. C. Kapteyn, C. Song, J. Miao, Y. Liu, and F. Salmassi:
    "Lensless diffractive imaging using tabletop, coherent, high harmonic soft x-ray beams"
    Phys. Rev. Lett., 99, 98103 (2007)
  7. H. Jiang, D. Ramunno-Johnson, C. Song, B. Amirbekian, Y. Kohmura, Y. Nishino, Y. Takahashi, T. Ishikawa, and J. Miao:
    "Nanoscale imaging of mineral crystals inside biological composite materials using x-ray diffraction microscopy"
    Phys. Rev. Lett., 100, 038103 (2008)
  8. J. Miao, R. L. Sandberg and C. Song:
    "Coherent Diffraction Imaging with X-rays"
    IEEE J. of Sel. Topics in Quantum Electronics 18, 399, (2011)
  9. J. Park, D. Nam, Y. Kohmura, M. Nagasono, Y. Jeon, J.-B. Lee, T. Ishikawa and C. Song:
    "Assessment of Radiation Damage in Single-shot Coherent Diffraction of DNA Molecules by EUV-FEL"
    Phys. Rev. E 86, 042901(2012)
  10. D. Nam, J. Park, M. Gallagher-Jones, S. Kim, S.-N. Kim, Y. Kohmura, H. Naitow, N. Kunishima, T. Yoshida, T. Ishikawa and C. Song:
    "Imaging fully hydrated whole cells by coherent x-ray diffraction microscopy"
    Phys. Rev. Lett. (in print 2013)

Lab Members

Principal Investigator

Makina Yabashi
Team Leader

Core Members

Eriko Nango
Research Scientist
Saori Maki
Research Scientist
Yoshinori Matsuura
Research Associate