Genomic Sciences Center Computational and Experimental Systems Biology Group Genome Annotation and Comparative Analysis Team Team Leader: Dr. Todd Taylor
Initial Gene Catalog of the Highly Disease-Related Human Chromosome 11 Has Been Completed
Do you have a history of diabetes or high-blood pressure in your family? As the aging of society continues, more people are becoming interested in and discussing genetic information. The first step to elucidating our genetic code, the successful completion of decoding the human genome sequence, was declared by the International Human Genome Sequencing Consortium in April 2003. This declaration meant that the DNA sequences, which hold the key to genetic information, were precisely determined. RIKEN Genomic Sciences Center (RIKEN GSC) played a central part of the international team, and has further continued to precisely decode human chromosome 11, which has high relevance to diseases such as diabetes and leukemia. They have formed a catalog that collects all the information on the structure and varieties of 1,524 genes. RIKEN GSC also developed an original gene detection program, which was used, along with experimental evidence, to successfully discover 34 new genes. The data derived from this research is expected to provide a platform for the detection of disease-related genes as well as for medical research in areas such as diagnosis and treatment. The research results were published in the March 23, 2006, issue of "Nature".
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