Cell Engineering Division (RIKEN BRC Cell Bank)
Head of Cell Engineering Division
Yukio NAKAMURA (M.D., Ph.D.)
Cell Engineering Division in RIKEN BioResource Center (BRC) was originally organized as the RIKEN Cell Bank in 1987. It is a unique, not-for-profit public organization for deposit, standardization, preservation, and distribution of cultured animal cell lines produced by life science community. We conduct not only banking of cell materials but also research and development related to cell engineering, such as establishment of novel human and animal cell lines and development of technology to culture primate pluripotent stem cells efficiently.
- Development of fundamental technologies relating to ES and iPS cells
- Development of technologies to induce differentiation from ES or iPS cells
- Development of technologies to establish cell lines possessing differentiation potential
- October 06, 2006
- A new production protocol for red blood corpuscles from cord blood
- Nakamura, Y., Hiroyama, T., Miharada, K., and Kurita, R.:
"Red blood cell production from immortalized progenitor cell line."
Int. J. Hematol. (in press) - Yoshino, K., Saijo, K., Noro, C., and Nakamura, Y.:
"Development of a simple method to determine the mouse strain from which cultured cell lines originated."
Interdisciplinary Bio Central 2: Article No. 14 (open access journal) doi: 10.4051/ibc.2010.2.4.0014 (2010) - Fujioka, T., Shimizu, N., Miyoshi, H., and Nakamura, Y.:
"Establishment of induced pluripotent stem cells from human neonatal tissues. "
Hum. Cell 23: 113-118 (2010) - Sudo, K., Yasuda, J., and Nakamura, Y.:
"Gene expression profiles of cryopreserved CD34+ human umbilical cord blood cells are related to their bone marrow reconstitution abilities in mouse xenografts."
Biochem. Biophys. Res. Commun. 397: 697-705 (2010) - Ishigaki, T., Sudo, K., Hiroyama, T., Miharada, K., Ninomiya, H., Chiba, S., Nagasawa, T., and Nakamura, Y.:
"Human hematopoietic stem cells can survive in vitro for several months. "
Adv. Hematol. 2009: ID936761 (open access journal) (2009) - Tamagawa, T., Ishiwata, I., Sato, K., and Nakamura, Y.:
"Induced in vitro differentiation of pancreatic-like cells from human amnion-derived fibroblast-like cells."
Hum. Cell 22: 55-63 (2009) - Danjoh, I., Sone, H., Sekiyama, S., Mizukoshi, K., Noda, N., Iimura, E., Nagayoshi, M., Saijo, K., Hiroyama, T., and Nakamura, Y.:
"Is parainfluenza virus a threatening virus for human cancer cell lines?"
Hum. Cell 22: 81-84 (2009) - Hiroyama, T., Miharada, K., Sudo, K., Danjo, I., Aoki, N., and Nakamura, Y.:
"Establishment of mouse embryonic stem cell-derived erythroid progenitor cell lines able to produce functional red blood cells."
PLoS ONE 3: e1544 (2008). - Sudo, K., Kanno, M., Miharada, K., Ogawa, S., Hiroyama, T., Saijo, K., and Nakamura, Y.:
"Mesenchymal progenitors able to differentiate into osteogenic, chondrogenic, and/or adipogenic cells in vitro are present in most primary fibroblast-like cell populations."
Stem Cells 25: 1610-1617 (2007) - Miharada, K., Hiroyama, T., Sudo, K., Nagasawa, T., and Nakamura, Y.:
"Efficient enucleation of erythroblasts differentiated in vitro from hematopoietic stem and progenitor cells."
Nat. Biotechnol. 24: 1255-1256 (2006)
Principal Investigator
- Yukio NAKAMURA
- Head
Staff Scientist
- Takashi HIROYAMA
- Senior Research Scientist
- Kaoru SAIJO
- Senior Technical Scientist
- Michiya NOGUCHI
- Technical Scientist
Postdoctoral Fellow
- Kazuhiro SUDO
- Contract Researcher
- Inaho DANJOH
- Contract Researcher
- Ryou KURITA
- Contract Researcher
- Yuko MIYAGI
- Postdoctoral Researcher
Technical Assistant
- Saeri OGAWA
- Technical Staff 2
- Tsuyoshi FUJIOKA
- Technical Staff 2
- Kanae KURITA
- Technical Staff 2
- Mariko NAGAYOSHI
- Technical Staff 2
- Emi IIMURA
- Technical Staff 2
- Naoko AOKI
- Technical Staff 2