Gene Discovery Research Group
Group Director
Kazuo SHINOZAKI (D.Sci.)
This research team is discovering Arabidopsis genes of which functions are linked to quantitative improvements in plants and those with new functions for minimizing the effects of the environmental stresses to achieve maximum productivity. We are attempting to elucidate genetic functions through a reverse genetic approach using gene destruction and transgenic overexpression. Other targets of research include genes that respond to environmental changes and stimuli and genes involved in metabolic regulation. We are also exploring new genes involved in improved productivity at the genome level using transcriptome and metabolome analyses, and are analyzing regulatory factors and signaling factors involved in the control of gene expression.
- Exploration and analysis of regulatory factors and signaling factors in environmental stress responses
- Exploration and use of genes involved in plant productivity using a reverse genetic approach
- Development of environmental stress resistance wheat and rice
- Exploration and use of genes involved in soft biomass engineering using Brachypodium distachyon
- R&D Programs for PSC
- March 19, 2007
- Gene Discovery Research Team of PSC identified the cellular signal transduction pathway mediated by a plant hormone, jasmonate, and a new protein kinase cascade MKK3-MPK6 that played a critical role in a defense-responding mechanism through jasmonate signaling.
- August 02, 2007
- Plant Gene Expression Research Team of PSC clarified that the CPC gene which produces root hair of Thales cress had been transformed via the evolutional process involving the WER gene, suppressing the growth of root hairs.
- March 03, 2008
- Genetic control of key defences
A new study shows how plants adapt to environmental changes, new ecological niches.
- July 01, 2008
- Open access to the world's first united gene map data bases of wheat and barley for the promotion of effective research and development
- December 02, 2008
- Identification of genes for two enzymes essential for the removal of active oxygen in chromosomes, promising better understanding of the function of plant superoxide dismutase, and quenching harmful active oxygen
- December 15, 2009
- Database of gene mutant phenotypes that encode chlorophyll proteins
- Schmutz, J., Cannon, S.B., Schlueter, J., Ma, J., Mitros, T., Nelson, W., Hyten, D.L., Song, Q., Thelen, J.J., Cheng, J., Xu, D., Hellsten, U., May, G.D., Yu, Y., Sakurai, T., Umezawa, T., Bhattacharyya, M.K., Sandju, D., Valliyodan, B., Lindquist, E., Peto, M., Grant, D., Shu, S., Goodstein, D., Barry, K., Futrell-Griggs, M., Abernathy, B., Du, j., Tian, Z., Zhu, L., Gill, N., Joshi, T., Libault, M., Sethuraman, A., Zhang, X-C., Shinozaki, K., Nguyen, H.T., Wing, R.A., Cregan, P., Specht, J., Grimwood, J., Rokhsar, D., Stacey, G., Shoemaker, R.C., and Jackson, S.A.:
"Genome sequence of the palaeopolyploid soybean."
Nature, 463,178-83 (2010) - Urano, K., Kurihara, Y., Seki, K., and Shinozaki, K.:
"'Omics' analyses of regulatory networks in plant abiotic stress responses."
Curr.Opin. Plant Biol., 13, 132-138 (2010) - Hirayama, T. and Shinozaki, K.:
"Research on plant abiotic stress responses in the post-genome era: past, present."
Plant J, 61, 1041-1062 (2010) - Kuromori, T., Miyaji, T., Yabuuchi, H., Shimizu, H., Sugimoto, E., Kamiya, A., Moriyama, Y., and Shinozaki, K.:
"ABC transporter AtABCG25 is involved in abscisic acid transport and responses."
Proc. Natl. Acad. Sci. USA, 109, 2361-2366 (2010) - Umezawa, T., Sugiyama, N., Mizoguchi, M., Hayashi, S., Myouga, F., Yamaguchi-Shinozaki, K., Ishihama, Y., Hirayama, T., and Shinozaki, K.:
"Type 2C protein phosphatases directly regulate abscisic acid-activated protein kinases in Arabidopsis."
Proc. Natl. Acad. Sci. USA, 106, 17588-93 (2009). - Urano, K., Maruyama, K., Ogata, Y., Morishita, Y., Takeda, M., Sakurai, N., Suzuki, H., Saito, K., Shibata, D., Kobayashi, M., Yamaguchi-Shinozaki, K., and Shinozaki, K.:
"Characterization of the ABA-regulated global responses to dehydration in Arabidopsis by metabolomics."
Plant J, 57. 1065-1078 (2009) - Myouga, F., Hosoda, C., Umezawa, T., Iizumi, H., Kuromori, T., Motohashi, R., Shono, Y., Nagata, N., Ikeuchi, M., and Shinozaki, K.:
"Heterocomplex of Arabidopsis chloroplast-targeted iron superoxide dismutases, FSD2 and FSD3, mediates defense against oxidative stress in chloroplast nucleoids and is essential for chloroplast development."
Plant Cell, 20, 3148-3162 (2008) - Umezawa, T., Sakurai, T., Totoki, Y., Toyoda, A., Seki, M., Ishiwata, A., Akiyama, K., Kurotani, A., Yoshida, T., Mochida, K., Kasuga, M., Todaka, D., Maruyama, K., Nakashima, K., Enju, A., Mizukado, S., Selina, A., Yoshiwara, K., Harada, K., Tsubokura, Y., Hayashi, M., Sato, S., Anai, T., Ishimoto, M., Funatsuki, H., Teraishi, M., Osaki, M., Shinano, T., Akashi, R., Sakaki, Y., Yamaguchi-Shinozaki, K., and Shinozaki, K.:
"Sequencing and analysis of approximately 40,000 soybean cDNA clones from a full-length enriched cDNA library."
DNA Res, 15. 333-346 (2008) - Fujita, M., Mizukado, S., Fujita, Y., Ichikawa, T., Nakazawa, M., Seki, M., Matsui, M., Yamaguchi-Shinozaki, K., and Shinozaki, K.:
"Identification of stress-tolerance-related transcription-factor genes via mini-scale Full-length cDNA over-eXpressor (FOX) gene hunting system."
Biochem. Biophys.Res.Commun. 364, 250-257 (2007) - Takahashi, F., Yoshida, R., Ichimura, K., Mizoguchi, T., Seo, S., Yonezawa, M., Maruyama, K., Yamaguchi-Shinozaki, K., and Shinozaki, K.:
"Dissecting the jasmonate signaling pathway by a novel MAP kinase cascade, MKK3-MPK6, in Arabidopsis."
Plant Cell, 19, 805-818 (2007)
Principal Investigator
- Kazuo SHINOZAKI
- Group Director
Members
- Takashi KUROMORI
- Senior Research Scientist
- Kiminori TOYOOKA
- Senior Research Scientist
- Keiichi MOCHIDA
- Senior Research Scientist
- Miki FUJITA
- Research Scientist
- Fumiyoshi MYOUGA
- Research Scientist
- Fuminori TAKAHASHI
- Research Scientist
- Kaoru URANO
- Research Scientist
- Kousuke HANADA
- Research Scientist
- Yuriko OSAKABE
- Research Scientist
- Mayuko SATO
- Technical Scientist
- Kumiko KONDO
- Special Postdoctoral Researcher
- Hironori TAKASAKI
- Postdoctoral Researcher
- Babak BEHNAM
- Postdoctoral Researcher
- Yosuke ISHIDA
- Junior Research Associate
- Yukiko UEHARA
- Technical Staff
- Yumiko TSUCHIYA
- Technical Staff
- Akiko ONOZUKA
- Technical Staff
- Saho MIZUKADO
- Technical Staff
- Mayumi WAKAZAKI
- Technical Staff
- Yuka MITANI
- Technical Staff
- Eriko SUGIMOTO
- Technical Staff
- Chihiro OHASHI
- Technical Staff
- Minami SHIMIZU
- Technical Staff