RIKEN Center for Genomic Medicine
Director, CGM
Michiaki KUBO (M.D., Ph.D.)
(acting director)
By systematic analysis of SNPs covering the entire genome, the Center for Genomic Medicine is investigating genes susceptible to various diseases, including atopic dermatitis, bronchial asthma, myocardial infarction, rheumatoid arthritis, osteoarthritis, diabetic nephropathy, obesity, and Crohn's disease as well as genes related to responses to interferon treatment of hepatitis C infection. To date, we have identified genes involved in the onset of myocardial infarction, rheumatoid arthritis, osteoarthritis, disc herniation, bronchial asthma and diabetic nephropathy.
The results of this research will be applied in the "personalized medicine", where an appropriate medication with the minimum risk of adverse reactions is provided to an individual patient. Furthermore, if we can isolate genes causative to various diseases whose etiology is unknown or little known, such information will be applied to the development of novel molecular-targeting drugs. Moreover, we hope to develop preventive techniques suitable for individuals, through a prior detection of a higher risk to certain diseases.
| Research Group for Genotyping | Michiaki KUBO (M.D., Ph.D.) | |
| Laboratory for Genotyping Development | Michiaki KUBO (M.D., Ph.D.) | |
| Laboratory for Biomarker Development | Hidewaki NAKAGAWA (M.D., Ph.D.) | |
| Research Group for Medical Informatics | Tatsuhiko TSUNODA (Ph.D.(Medicine) & Ph.D.(Eng.)) | |
| Laboratory for Statistical Analysis | Atsushi TAKAHASHI (Ph.D.) | |
| Laboratory for Medical Informatics | Tatsuhiko TSUNODA (Ph.D.(Medicine) & Ph.D.(Eng.)) | |
| Research Group for Pharmacogenomics | Michiaki KUBO (M.D., Ph.D.) | |
| Laboratory for Pharmacogenetics | Taisei MUSHIRODA (Ph.D.) | |
| Laboratory for International Alliance | Michiaki KUBO (M.D., Ph.D.) | |
| Research Group for Disease-causing Mechanism | Toshihiro TANAKA (M.D., Ph.D.) | |
| Laboratory for Cardiovascular Diseases | Toshihiro TANAKA (M.D., Ph.D.) | |
| Laboratory for Autoimmune Diseases | Kazuhiko YAMAMOTO (M.D., Ph.D.) | |
| Laboratory for Bone and Joint Diseases | Shiro IKEGAWA (M.D., Ph.D.) | |
| Laboratory for Respiratory Diseases | Mayumi TAMARI (M.D., Ph.D.) | |
| Laboratory for Endocrinology and Metabolism | Shiro MAEDA (M.D., Ph.D.) | |
| Laboratory for Digestive Diseases | Kazuaki CHAYAMA (M.D., Ph.D.) | |