瀧本 真徳Masanori TAKIMOTO
Birth: 12 June, 1970
Tel: +81-(0)48-467-9390
Fax: +81-(0)48-462-4665
E-mail:
| 瀧本 真徳 Masanori TAKIMOTO Birth: 12 June, 1970 Tel: +81-(0)48-467-9390 Fax: +81-(0)48-462-4665 E-mail: |
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| Curriculum Vitae | ||
| >> Japanese | ||
| Education: | ||
| 1993 | B.Sc. | Faculty of Pharmaceutical Sciences, Hokkaido University (Japan) |
| 1995 | M.Sc. | Graduate School of Pharmaceutical Sciences, Hokkaido University (Japan) (Supervisor: Prof. Miwako Mori) |
| 1998 | Ph.D. | Graduate School of Pharmaceutical Sciences, Hokkaido University (Japan) (Supervisor: Prof. Miwako Mori) |
| Research and professional experience: | |
| 1995-1998 | Predoctoral Research Fellow of the Japan Society for the Promotion of Science |
| 1998-1999 | Postdoctoral Fellow of Uehara Memorial Foundation Department of Chemistry, University of Toronto (Prof. Mark Lautens group) |
| 1999 - Sept. 2006 |
Assistant Professor Graduate School of Pharmaceutical Sciences, Hokkaido University |
| Oct. 2006 |
Research Scientist, Organometallic Chemistry Laboratory, RIKEN |
| 2009- | Senior Research Scientist, Organometallic Chemistry Laboratory, RIKEN |
| Honor: | |
| 2006 | The Pharmaceutical Society of Japan Award for Young Scientists '06 |
| Original Publications | |
| · | Masanori Takimoto, Takashi Mizuno, Miwako Mori, and Yoshihiro Sato; Nickel-mediated cyclization of enynes under an atmosphere of carbon dioxide. Tetrahedron 2005, 62, 7589-7597. |
| · | Masanori Takimoto, Yuuki Kajima, Yoshihiro Sato, and Miwako Mori; Nickel-Catalyzed Enantioselective Three-Component Coupling of Bis-1,3-dienes, aldehyde, and Dimethylzinc. J. Org. Chem. 2005, 70, 8605-8608. |
| · | Masanori Takimoto, Mitsunobu Kawamura, Miwako Mori, and Yoshihiro Sato; Nickel-Catalyzed Regio- and Stereoselective Double Carboxylation of Trimethylsilylallene under an Atmosphere of Carbon Dioxide and Its Application to the Synthesis of Chaetomellic Acid A Anhydride. Synlett 2005, 2019-2022. |
| Masanori Takimoto, Takashi Mizuno, Yoshihiro Sato, and Miwako Mori; Nickel-mediated carboxylative cyclization of enynes. Tetrahedron Lett. 2005, 46, 5173-5176. | |
| · | Kazuya Shimizu, Masanori Takimoto, Yoshihiro Sato, and Miwako Mori; Nickel-Catalyzed Regioselective Synthesis of Tetrasubstituted Alkene Using Alkylative Carboxylation of Disubstituted Alkyne. Org. Lett. 2005, 7, 195-197. |
| · | Masanori Takimoto, Yoichi Nakamura, Kaoru Kimura, and Miwako Mori; Highly Enantioselective Catalytic Carbon Dioxide Incorporation Reaction: Nickel-Catalyzed Asymmetric Carboxylative Cyclization of Bis-1,3-dienes. J. Am. Chem. Soc. 2004, 126, 5956-5957. |
| · | Masanori Takimoto, Mitsunobu Kawamura, and Miwako Mori; Nickel-Mediated Regio- and Stereoselective Carboxylation of Trimethylsilylallene under an Atmosphere of Carbon Dioxide. Synthesis 2004, 791-795. |
| · | Masanori Takimoto, Mitsunobu Kawamura, and Miwako Mori; Nickel(0)-Mediated Sequential Addition of Carbon Dioxide and Aryl Aldehydes into Terminal Allenes. Org. Lett. 2003, 5, 2599-2601. |
| · | Kazuya Shimizu, Masanori Takimoto, and Miwako Mori; Novel Synthesis of Heterocycles Having a Functionalized Carbon Center via Nickel-Mediated Carboxylation. Org. Lett. 2003, 5, 2323-2325. |
| · | Miwako Mori, Nozomi Saito, Daisuke Tanaka, Masanori Takimoto, and Yoshihiro Sato; Novel Alkenylative Cyclization Using a Ruthenium Catalyst. J. Am. Chem. Soc. 2003, 125, 5606-5607. |
| · | Masanori Takimoto and Miwako Mori; Novel Catalytic CO2 Incorporation Reaction: Nickel-Catalyzed Regio- and Stereoselective Ring-Closing Carboxylation of Bis-1,3-dienes. J. Am. Chem. Soc. 2002, 124, 10008-10009. |
| · | Masanori Takimoto, Kazuya Shimizu, and Miwako Mori; Nickel-Promoted Alkylative or Arylative Carboxylation of Alkynes. Org. Lett. 2001, 3, 3345-3347. |
| · | Masanori Takimoto and Miwako Mori; Cross-Coupling Reaction of Oxo-π-allylnickel Complex Generated from 1,3-Diene under am Atmosphere of Carbon Dioxide. J. Am. Chem. Soc. 2001, 123, 2895-2896. |
| · | Miwako Mori, Yuji Kozawa, Mayumi Nishida, Makiko Kanamaru, Seiko Onozuka, and Masanori Takimoto; Synthesis of Carbapenam Skeletons Using a Ruthenium-Catalyzed Cyclization. Organic Letters 2000, 2, 3245-3247. |
| · | Yoshihiro Sato, Masanori Takimoto, and Miwako Mori; Total Synthesis of Prostaglandin F2α Using Nickel-Catalyzed Stereoselective Cyclization of 1,3-Diene and Tethered Aldehyde via Transmetalation of Nickelacycle with Diisobutylaluminum Acetylacetonate. Chem Pharm. Bull. 2000, 48, 1753-1760. |
| ・ | Yoshihiro Sato, Masanori Takimoto, and Miwako Mori; Further Studies on Nickel-Promoted or -Catalyzed Cyclization of 1,3-Diene and a Tethered Carbonyl Group. J. Am. Chem. Soc. 2000, 122, 1624-1634. |
| · | Masanori Takimoto, Yoshiko Hiraga, Yoshihiro Sato, and Miwako Mori; Nickel-Catalyzed Regio- and Stereoselective Synthesis of Homoallyl Alcohol Derivatives from Diene and Aldehyde. Tetrahedron Lett. 1998, 39, 4543-4546. |
| · | Yoshihiro Sato, Masanori Takimoto, and Miwako Mori; Nickel-Catalyzed Regio- and Stereoselective Synthesis of Homoallyl Alcohol Derivatives from Diene and Aldehyde. Tetrahedron Lett. 1998, 39, 4543-4546. |
| · | Yoshihiro Sato, Masanori Takimoto, and Miwako Mori; Total Synthesis of Prostaglandin F2α via Nickel-Promoted Stereoselective Cyclization of 1,3-Diene and Aldehyde. Synlett 1997, 734-736. |
| · | Yoshihiro Sato, Masanori Takimoto, and Miwako Mori; Remarkable Regio-Controlled Effect of 1,3-Diene as a Ligand on Nickel-Promoted Cyclization. Tetrahedron Lett. 1996, 37, 887-890 |
| · | Yoshihiro Sato, Masanori Takimoto, and Miwako Mori; Novel Stereoselective Cyclization via π-Allylnickel Complex Generated from 1,3-Diene and Hydride Nickel Complex. J. Am. Chem. Soc. 1994, 116, 9771-9772 |
| Reviews & Books | |
| · | Masanori Takimoto and Miwako Mori; Nickel-mediated and -catalyzed Carboxylation. In Modern Organonickel Chemistry; Yoshinao Tamaru Ed.; Wiley-VCH: Weinheim, 2005, pp 205-223. |
| · | Miwako Mori, Yuji Kozawa, and Masanori Takimoto; Novel Synthesis of Carbapenams Using Transition Metals. 有機合成化学協会誌 2003, 61, 1065-1072. |
| · | 佐藤 美洋, 瀧本 真徳, 森 美和子; ニッケル触媒を用いる1,3-ジエンとカルボニル基との立体選択的環化反応の開発と有機合成への応用. 有機合成化学協会誌 2001, 59, 576-588. |
| 略歴 | >> English |
| 1993年3月 | 北海道大学 薬学部薬学科 卒業 生体分子構造学教室（森美和子 教授） |
| 1995年3月 | 北海道大学大学院 薬学研究科 修士課程（製薬化学専攻）修了 生体分子構造学教室（森美和子 教授） |
| 1995年4月 ～1998年3月 |
日本学術振興会特別研究員（北海道大学大学院薬学研究科） |
| 1998年3月 | 北海道大学大学院薬学研究科博士課程（製薬化学専攻）修了 精密合成化学教室（森美和子 教授） 博士（薬学）取得 『ニッケル触媒を利用した新規立体選択的環化反応の開発』 |
| 1998年4月 | カナダ・トロント大学化学科 博士研究員 (Mark Lautens教授） |
| 1999年4月 | 北海道大学大学院薬学研究科 助手 （創薬化学専攻 精密合成化学分野 森美和子教授、2004年4月－佐藤美洋教授） |
| 2006年10月 |
独立行政法人 理化学研究所 研究員 （中央研究所 侯有機金属化学研究室） |
| 2009年4月 ～現在 |
独立行政法人 理化学研究所 専任研究員 （基幹研究所 侯有機金属化学研究室） |
| 受賞 | |
| 2006年3月 | 平成１８年度 日本薬学会奨励賞 |