RIKEN Baton Zone Program Bio-monomer Production Laboratory

We are studying the following in order to produce bio-butadiene by microorganisms and realize bio-polybutadiene.

• ①Improve the activity of butadiene-producing microorganisms.
  The enzyme of the key reaction is highly activated by the enzyme engineering method, and at the same time, the intracellular metabolism is optimized by using the synthetic biology technology to improve the productivity.
• ②Purification of biobutadiene produced in the gas phase of the fermenter
  By-products of fermentation may include polymerization inhibitors. Based on the polymerization technology, we will develop a concentration/purification process and develop a process that can produce commercially viable butadiene.

[Integrated Collaborative Research with Zeon Corporation and The Yokohama Rubber Co., Ltd.]

Main Research Fields

• Engineering

Related Research Fields

• Chemistry
• Biology
• Biofunction/Bioprocess

Keywords

• enzyme engineering
• synthetic biology
• fermentation
• microorganism
• butadiene