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RIKEN Baton Zone Program Advanced Electron Microscope Development Unit

Unit Leader: Koji Yonekura (Ph.D.)

Research Summary

Koji  Yonekura(Ph.D.)

We address R & D of the advanced cryo-electron microscopy through combining the knowledge of JEOL on the electron microscope with the elemental technologies fostered by operation and development of SPring-8/SACLA.

Main Research Fields

  • Biological Sciences

Related Research Fields

  • Chemistry
  • Biology


  • Advanced Cryo-Electron Microscopy

Selected Publications

  • 1. Maki-Yonekura, S., Hamaguchi, T., Naitow, H., Takaba, K. and Yonekura, K.:
    "Advances in Cryo-EM and ED with a Cold-Field Emission Beam and Energy Filtration --- Refinements of the CRYO ARM 300 System in RIKEN SPring-8 Center ---"
    In press.
  • 2. Naitow, H., Hamaguchi, T., Maki-Yonekura, S., Isogai, M., Yoshikawa, N. and Yonekura, K.:
    "Apple latent spherical virus structure with stable capsid frame supports quasi-stable protrusions expediting genome release"
    Commun. Biol. 3: 488 (2020).
  • 3. Takaba, K., Maki-Yonekura, S. and Yonekura, K.:
    "Collecting large datasets of rotational electron diffraction with ParallEM and SerialEM"
    J. Struct. Biol. 211: 107549 (2020).
  • 4. Hamaguchi, T. and Yonekura, K.:
    "Tidy up cryo-EM sample grids with 3D printed tools"
    J. Struct. Biol. 209 (1), 107414 (2020).
  • 5. Hamaguchi T., Maki-Yonekura S., Naitow H., Matsuura Y., Ishikawa T. and Yonekura K.:
    "A new cryo-EM system for single particle analysis"
    J. Structl. Biol. 207: 40-48 (2019).
  • 6. Yonekura K., Ishikawa T. and Maki-Yonekura S.:
    "A new cryo-EM system for electron 3D crystallography"
    J. Structl. Biol. 206: 243-253 (2019).
  • 7. Guzmán-Afonso C., Hong Y.-L., Colaux H., Iijima H., Saitow A., Fukumura T., Aoyama Y., Motoki S., Oikawa T., Yamazaki T., Yonekura K. and Nishiyama Y.:
    "Understanding hydrogen bonding structure of molecular crystals by electron-and NMR-nanocrystallography"
    Nat. Commun. 10: 3537 (2019).

Lab Members

Principal investigator

Koji Yonekura
Unit Leader

Contact Information

1-1-1 Kouto, Sayo-cho Sayo-gun, Hyogo 679-5148 Japan
Email: yone [at] spring8.or.jp