Research Summary

Selected Publications

Papers with an asterisk(*) are based on research conducted outside of RIKEN.

• 1.Okano H, Sasaki E, Yamamori T, Iriki A, Shimogori T, Yamaguchi Y, Kasai K, Miyawaki A.
  "Brain/MINDS: A Japanese National Brain Project for Marmoset Neuroscience"
  Neuron. 2016, 92, 582-590.
• 2.*Sato K, Oiwa R, Kumita W, Henry R, Sakuma T, Ito R, Nozu R, Inoue T, Katano I, Sato K, Okahara N, Okahara J, Shimizu Y, Yamamoto M, Hanazawa K, Kawakami T, Kametani Y, Suzuki R, Takahashi T, Weinstein EJ, Yamamoto T, Sakakibara Y, Habu S, Hata J, Okano H, Sasaki E.
  "Generation of a Nonhuman Primate Model of Severe Combined Immunodeficiency Using Highly Efficient Genome Editing"
  Cell Stem Cell. 7;19:127-38
• 3.Okano H, Miyawaki A, Kasai K.: Brain/MINDS:
  "Brain/MINDS: brain-Mapping project in Japan"
  Philos Trans R Soc Lond B Biol Sci. 2015 May 19;370(1668). pii: 20140310. doi: 10.1098/rstb.2014.0310.
• 4.Izpisua Belmonte JC, Callaway EM, Churchland P, Caddick SJ, Feng G, Homanics GE, Lee K-F, Leopold DA, Miller CT, Mitchell JF, Mitalipov F, Moutri AR, Movshon JA, Okano H, Reynolds JH, Ringach D, Sejnowski TJ, Silva AC, Strick PL, Wu J, Zhang F. (in alphabetical order):
  "Brains, genes and Primates"
  Neuron. 2015 May 6;86(3):617-31. doi: 10.1016/j.neuron.2015.03.021.
• 5.*Hikishima K, Ando K, Yano R, Kawai K, Komaki Y, Inoue T, Itoh T, Yamada M, Momoshima S, Okano HJ, Okano H.
  "Parkinson Disease: Diffusion MR Imaging to Detect Nigrostriatal Pathway Loss in a Marmoset Model Treated with 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine"
  Radiology. 2015 May;275(2):430-7. doi: 10.1148/radiol.14140601. Epub 2015 Jan 15.
• 6.*Kuwako K, Kawase S, Nishimoto Y, Okano H.:
  "Cadherin-7 regulates mossy fiber connectivity in the cerebellum"
  Cell Reports, 9(1):311-323, 2014.
• 7.*Bae B-I, Tietjen I, Atabay KD, Evrony GD, Johnson MB, Asare E, Murayama A, Im K, Crosier M, Lisgo SN, Lindsay S, Šestan N, Bernard S. Chang BS, Barkovich J, Grant E, Topçu M, Politsky J, Okano H, Piao X, and Walsh CA:
  "Evolutionarily Dynamic Alternative Splicing of GPR56 Regulates Regional Cerebral Cortical Patterning"
  Science 343 (6172): 764-768, 2014.
• 8.*Naka-Kaneda H, Nakamura S, Igarashi M, Aoi H, Kanki H, Tsutsumi S, Aburatani H, Shimazaki T and Okano H:
  "The miR-17/106-p38 axis is a key regulator of the neurogenic-to-gliogenic competence transition in developing neural stem/progenitor cells"
  Proc.Natl.Acad.Sci.USA 111(4):1604-1609, 2014
• 9.*Bundo M, Toyoshima M, Okada Y, Akamatsu W, Ueda J, Nemoto-Miyauchi T, Sunaga F, Toritsuka M, Ikawa D, Kakita A, Kato M, Kasai K, Kishimoto T, Nawa H, Okano H, Yoshikawa T, Kato T, and Iwamoto K:
  "Increased L1 Retrotransposition in the neuronal genome in Schizophrenia"
  Neuron 81(2):306-313, 2014.
• 10.*Sasaki E, Suemizu H, Shimada A, Hanazawa K, Oiwa R, Kamioka M, Sotomaru Y, Hirakawa R, Eto T, Shiozawa S, Maeda T, Ito R, Kito C, Yagihashi C, Kawai K, Miyoshi H, Tanioka Y, Tamaoki N, Habu S, Okano H, Nomura T.:
  "Generation of transgenic non-human primates with germ line transmission"
  Nature, 459(7246): 523-527, 2009. (*H. Okano is the corresponding author in this paper)

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