RIKEN Center for Brain Science Rhythm-Based Brain Information Processing Unit

Unit Leader: Keiichi Kitajo (Ph.D.)

Japanese Page

Research Summary

We investigate neural dynamics mediating adaptive and emergent brain functions. Specifically, we focus on functional roles of nonlinear neural dynamics such as oscillations and synchrony in perceptual, motor, cognitive, and communication processes in humans. We take manipulative approaches such as tES(transcranial electrical stimulation), TMS (Transcranial magnetic stimulation)-EEG (Electroencephalography), and neurofeedback to show causal roles of nonlinear neural dynamics in brain functions. We will find extensive applications of our approaches for stoke rehabilitation.

Main Research Fields

Complex Systems

Related Research Fields

Biological Sciences

Keywords

Recording brain activity
Brain stimulation
Nonlinear neural dynamics

Selected Publications

1. Yuka O.Okazaki, Yuji Mizuno, Keiichi Kitajo.:
"Probing dynamical cortical gating of attention with concurrent TMS-EEG."
Scientific Reports, 10, 4959, 1-10, doi: 10.1038/s41598-020-61590-2, 2020.
2. Hiromichi Suetani, Keiichi Kitajo.:
"A manifold learning approach to mapping individuality of human brain oscillations through beta-divergence."
Neuroscience Research, 4373, 1-9, doi: 10.1016/j.neures.2020.02.004, 2020.
3. Kei-ichi Ueda, Yasumasa Nishiura, Keiichi Kitajo.:
"Mathematical mechanism of state-dependent phase resetting properties of alpha rhythm in the human brain."
Neuroscience Research, 4387, 1-13, doi: 10.1016/j.neures.2020.03.007, 2020.
4. Yue Wei, Yuka O. Okazaki, Richard HY So, Winnie C Chu, Keiichi Kitajo.:
"Motion sickness-susceptible participants exposed to coherent rotating dot patterns show excessive N2 amplitudes and impaired theta-band phase synchronization."
NeuroImage, 202, 116028, 1-13, doi: 10.1016/j.neuroimage.2019.116028, 2019.
5. Sarah Glim, Yuka Okazaki, Yumi Nakagawa, Yuji Mizuno, Takashi Hanakawa, Keiichi Kitajo.:
"Phase-amplitude coupling of neural oscillations can be effectively probed with concurrent TMS-EEG."
Neural Plasticity, 6263907, 1-13, doi: 10.1155/2019/6263907, 2019.
6. Teiji Kawano, Noriaki Hattori, Yutaka Uno, Keiichi Kitajo, Megumi Hatakenaka, Hajime Yagura, Hiroaki Fujimoto, Tomomi Yoshioka, Michiko Nagasako, Hironori Otomune, Ichiro Miyai.:
"Large-scale phase synchrony reflects clinical status after stroke: An EEG study."
Neurorehabilitation & Neural Repair, 31, 6, 561-570, doi: 10.1177/1545968317697031, 2017.
7. Takafumi Kajihara, Muhammad Nabeel Anwar, Masahiro Kawasaki, Yuji Mizuno, Kimitaka Nakazawa, Keiichi Kitajo.:
"Neural dynamics in motor preparation: From phase-mediated global computation to amplitude-mediated local computation."
NeuroImage, 118, 445-455, doi:10.1016/j.neuroimage.2015.05.032, 2015.
8. Keiichi Kitajo, Takashi Hanakawa, Risto J. Ilmoniemi and Carlo Miniussi.:
"A contemporary research topic: Manipulative approaches to human brain dynamics."
Frontiers in Human Neuroscience, 9:118. doi:10.3389/fnhum.2015.00118, 2015.
9. Muhammad Nabeel Anwar, Muhammad Samran Navid, Mushtaq Khan, Keiichi Kitajo.:
"A possible correlation between performance IQ, visuomotor adaptation ability and mu suppression"
Brain Research, 1603, 84-93,doi:10.1016/j.brainres.2015.01.045, 2015.
10. Masahiro Kawasaki, Yutaka Uno, Jumpei Mori, Kenji Kobata, Keiichi Kitajo.:
"Transcranial magnetic stimulation-induced global propagation of transient phase resetting associated with directional information flow."
Frontiers in Human Neuroscience, 8:173, doi: 10.3389/fnhum.2014.00173, 2014.

Lab Members

Principal investigator

Keiichi Kitajo: Unit Leader

Core members

Takuro Zama: Research Scientist
Gaochao Cui: Research Scientist
Takayuki Onojima: Special Postdoctoral Researcher
Yumi Shikauchi: Visiting Researcher
Kaori Maeda: Technical Staff II

Contact Information

2-1 Hirosawa, Wako, Saitama 351-0198, Japan