Research Summary

Selected Publications

• 1. Chhipi-Shrestha, J.K., Schneider-Poetsch, T., Suzuki, T., Mito, M., Khan, K., Dohmae, N., Iwasaki, S., Yoshida, M.:
  "Splicing modulators elicit global translational repression by condensate-prone proteins translated from introns."
  Cell Chem. Biol. 29(2), 259-275 (2022)
• 2. Yoshimoto, R., Chhipi-Shrestha, J.K., Schneider-Poetsch, T., Furuno, M., Burroughs, A.M., Noma, S., Suzuki, H., Hayashizaki, Y., Mayeda, A., Nakagawa, S., Kaida, D., Iwasaki, S., Yoshida, M.:
  "Spliceostatin A interaction with SF3B1 limits U1 snRNP availability and causes premature cleavage and polyadenylation."
  Cell Chem. Biol. 28(9), 1356-1365.e4. (2021)
• 3. Kobayashi, H., Hatakeyama, H., Nishimura, H., Yokota, M., Suzuki, S., Tomabechi, Y., Shirouzu, M., Osada, H., Mimaki, M., Goto, Y., Yoshida, M.:
  "Chemical reversal of abnormalities in cells carrying mitochondrial DNA mutations."
  Nat. Chem. Biol. 17(3), 335-343 (2021)
• 4. Han, P., Shichino, Y., Schneider-Poetsch, T., Mito, M., Hashimoto, S., Udagawa, T., Kohno, K., Yoshida, M., Mishima, Y., Inada, T., Iwasaki, S.:
  "Genome-wide survey of ribosome collision."
  Cell Rep. 31(5), 107610 (2020)
• 5. Ling, F., Bradshaw, E., Yoshida, M.:
  "Prevention of mitochondrial genomic instability in yeast by the mitochondrial recombinase Mhr1."
  Sci. Rep. 9(1), 5433 (2019)
• 6. Schneider-Poetsch, T., Yoshida, M.:
  "Along the central dogma-controlling gene expression with small molecules."
  Annu. Rev. Biochem. 87, 391-420 (2018).
• 7. Piotrowski, J.S., Li, S.C., Deshpande, R., Simpkins, S.W., Nelson, J., Yashiroda, Y., Barber, J.M., Safizadeh, H., Wilson, E., Okada, H., Gebre, A.A., Kubo, K., Torres, N., Leblanc, M.B., Andrusiak, K., Okamoto, R., Yoshimura, M., van Leeuwen, J., Shirahige, K., Baryshnikova, A., Brown, G., Saito, T., Costanzo, M., Andrews, B., Ohya, Y., Osada, H., Yoshida, M., Myers, C.L., Boone, C.:
  "Functional annotation of chemical libraries across diverse biological processes."
  Nat. Chem. Biol. 13(9), 982-993 (2017)
• 8. Yoshimoto, R., Kaida, D., Furuno, M., Burroughs, A.M., Noma, S., Suzuki, H., Kawamura, Y., Hayashizaki, Y., Mayeda, A., Yoshida, M.:
  "Global analysis of pre-mRNA subcellular localization following splicing inhibition by spliceostatin A."
  RNA 23(1), 47-57 (2017)
• 9. Vo, T.V., Das, J., Meyer, M.J., Cordero, N.A., Akturk, N., Wei, X., Fair, B.J., Degatano, A.G., Fragoza, R., Liu, L.G., Matsuyama, A., Trickey, M., Horibata, S., Grimson, A., Yamano, H., Yoshida, M., Roth, F.P., Pleiss, J.A., Xia, Y., Yu, H.:
  "A proteome-wide fission yeast interactome reveals network evolution principles from yeasts to human."
  Cell 164, 310-323 (2016)
• 10. Ito, A., Shimazu, T., Maeda, S., Shah, A.A., Tsunoda, T., Iemura, S.-I., Natsume, T., Suzuki, T., Motohashi, H., Yamamoto, M., and Yoshida, M.:
  "The subcellular localization and activity of cortactin is regulated by acetylation and interaction with Keap1."
  Sci. Signal. 8, ra120 (2015)

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