Research Summary

Selected Publications

• 1.Jang, J.-P, Nogawa, T., Futamura, Y., Shimizu, T., Hashizume, D., Takahashi, S., Jang J.-H., Ahn, J.S., and Osada, H.:
  "Octaminomycins A and B, cyclic octadepsipeptides active against Plasmodium falciparum."
  J. Nat. Prod., 80, 134-140 (2017).
• 2.Jang, J.-P, Takahashi, S., Futamura, Y., Nogawa, T., Jang, J.-H., Ahn, J.S., and Osada, H.:
  "RK-144171, a new benadrostin derivative produced by Streptomyces sp. RK88-1441."
  J. Antibiot., 70, 102-104 (2017).
• 3.Kim, J., Ko, S.-K., Kim, H.-M., Kim, G.H., Son, S., Kim, G.S., Hwang, G.J., Jeon, E.S., Shin, K.-S., Ryoo, I,-J., Hong, Y.-S., Oh, H., Lee, K.H., Soung, N.K., Hashizume, D., Takahashi, S., Kim, B.Y., Osada, H. Jang, J.-H., Ahn, J.S.:
  "Stachybotrysin, an osteoclast differentiation inhibitor from a marine-derived fungus Stachybotrys sp. KCB13F013."
  J. Nat. Prod., 79, 2703-2708 (2016).
• 4.Kato, N., Nogawa, T., Hirota, H., Jang, J.-H., Takahashi, S., Ahn, J.S., Osada, H.:
  "A new enzyme involved in the control of the stereochemistry in the decalin formation during equisetin biosynthesis."
  Biochem. Biophys. Res. Commun. 460, 210-215 (2015).
• 5.Kim, J.W., Ko, S.-K., Son, S., Shin, K.-S., Ryoo, I.-J., Hong, Y.-S., Oh, H., Hwang, B.Y., Hirota, H., Takahashi, S., Kim B.Y., Osada, H., Jang, J.H., Ahn, J.S.:
  "Haenamindole, an unusual diketopiperazine derivative from a marine-derived Penicillium sp. KCB12F005."
  Bioorg. Med. Chem. Lett. 25, 5398-5401 (2015).
• 6.Jang, J.-P., Nogawa, T., Uramoto, M., Okano, A., Futamura, Y., Shimizu, T., Takahashi, S., Jang, J.-H., Ahn, J.S., and Osada, H.:
  "RK270A-C, new oxindole derivatives isolated from a microbial metabolites fraction library of Streptomyces sp. RK85-270."
  J. Antibiot. 68, 293-295 (2015).
• 7.Oh, M., Jang, J.-H., Choo, S.-J., Kim, S.-O., Kim, J.W., Ko, S.-K., Soung, N.-K., Lee, J.-S., Kim, C.-J., Oh, H., Hong, Y.-S., Ueki, M., Hirota, H., Osada, H., Kim, B.Y., and Ahn, J.S.:
  "Boseongazepines A-C, Pyrrolobenzodiazepine Derivatives from a Streptomyces sp. 11A057."
  Bioorg. Med. Chem. Lett. 24, 1802-1804 (2014).
• 8.Asami, Y., Jang, J.-H., Soung, N.-K., He, L., Moon, D.O., Kim, J.W., Oh, H., Muroi, M., Osada, H., Kim, B.Y., and Ahn, J.S.:
  "Protuboxepin A, a marine fungal metabolite, inducing metaphase arrest and chromosomal misalignment in tumor cells."
  Bioorg. Med. Chem. 20, 3799-3806 (2012).
• 9.Asami, Y., Jang, J.-H., Oh, H., Sohn, J.H., Kim, J.W., Moon, D.O., Kwon, O., Kawatani, M., Osada, H., Kim, B.Y., and Ahn, J.S.:
  "Violaceols function as actin inhibitors inducing cell shape elongation in fibroblast cells."
  Biosci. Biotechnol. Biochem. 76, 1431-1437 (2012).
• 10.Jang, J.-H., Asami, Y., Jang, J.-P., Kim, S.O., Moon, D.O., Shin, K.S., Hashizume, D., Muroi, M., Saito, T., Oh, H., Kim, B.Y., Osada, H., and Ahn, J.S.:
  "Fusarisetin A, an Acinar Morphogenesis inhibitor from a soil fungus, Fusarium sp. FN0180326."
  J. Am. Chem. Soc, 133, 6865-6867 (2011).

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