Research Summary

Selected Publications

Papers with an asterisk(*) are based on research conducted outside of RIKEN.

• 1.Okada T., Takahashi S., Ishida A., and Ishigame H.:
  "In vivo multiphoton imaging of immune cell dynamics."
  Pflugers Arch – Eur J Physiol. 68, 1793-1801. (2016)
• 2.Shinnakasu R., Inoue T., Kometani K., Moriyama S., Adachi Y., Nakayama M., Takahashi Y., Fukuyama H., Okada T., and Kurosaki T.:
  "Regulated selection of germinal-center cells into the memory B cell compartment."
  Nat Immunol. 17, 861-869. (2016)
• 3.Kitano M., Yamazaki C., Takumi A., Ikeno T., Hemmi H., Takahashi N., Shimizu K., Fraser S.E., Hoshino K., Kaisho T., and Okada T.:
  "Imaging of the cross-presenting dendritic cell subsets in the skin-draining lymph node."
  Proc Natl Acad Sci U S A. 13, 1044-1049. (2016)
• 4.Moriyama S., Takahashi N., Green J.A., Hori S., Kubo M., Cyster J.G., Okada T.
  "Sphingosine-1-phosphate receptor 2 is critical for follicular helper T cell retention in germinal centers."
  J Exp Med. 211, 297-305. (2014)
• 5.Okada T., Moriyama S., and Kitano M.:
  "Differentiation of germinal center B cells and follicular helper T cells as viewed by tracking Bcl6 expression dynamics."
  Immunol Rev. 247: 120-132 (2012)
• 6.Hirata E., Yukinaga H., Kamioka Y., Arakawa Y., Miyamoto S., Okada T., Sahai E., and Matsuda M.:
  "In vivo fluorescence resonance energy transfer imaging reveals differential activation of Rho-family GTPases in glioblastoma cell invasion."
  J Cell Sci. 125: 858-868 (2012)
• 7.Kitano M., and Okada T.:
  "Four-dimensional tracking of lymphocyte migration and interactions in lymph nodes by two-photon microscopy."
  Methods Enzymol. 506: 437-454 (2012)
• 8.Kitano M., Moriyama S., Ando Y., Hikida M., Mori Y., Kurosaki T., and Okada T.:
  "Bcl6 protein expression shapes pre-germinal center B cell dynamics and follicular helper T cell heterogeneity."
  Immunity. 34: 961-72 (2011)
• 9.*Allen, C.D., Okada, T., Tang, H.L., and Cyster, J.G.:
  "Imaging of germinal center selection events during affinity maturation."
  Science, 315, 528-531, (2007)
• 10.*Okada, T., Miller, M.J., Parker, I., Krummel, M.L., Neighbors, M., Hartley, S.B., O’Garra, A., Cahalan, M.D., and Cyster, J.G.:
  "Antigen-engaged B cells undergo chemotaxis toward the T zone and form motile conjugates with helper T cells."
  PLoS Biology 3: 1047-1061(e150) (2005)

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