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Medical Sciences Innovation Hub Program Analytics Platform Development Group

Group Director: Kazuhiro Sakurada (Ph.D.)

Research Summary

Kazuhiro  Sakurada(Ph.D.)

Personalized medicine is a new paradigm that represent a shift from a statistical abstraction of the patients toward the view that each patient is unique.
Our laboratory conducts research with the goal of establishing a concept for understanding and predicting disease and life phenomena by utilizing medical data and lifelog data. We flexibly apply the new concept on machine learning, network and statistics to understand life event and to establish personalized medicine.

Main Research Fields

  • Biological Sciences

Related Research Fields

  • Informatics
  • Mathematical & Physical Sciences
  • Biology
  • Medicine, Dentistry & Pharmacy
  • Frontiers of informatics
  • Biological Science
  • Basic medicine


  • Lifesystem dynamics
  • Machine learning
  • Systems Biology
  • Bioinformatics

Selected Publications

  • 1.Kawakami E, Nakaoka S, Ohta T, Kitano H.:
    “Weighted enrichment method for prediction of transcription regulators from transcriptome and global chromatin immunoprecipitation data.”
    Nucleic Acids Res 44, 5010-21 (2016)
  • 2.Kawakami E, Singh VK, Matsubara K, Ishii T, Matsuoka Y, Hase T, Kulkarni P, Siddiqui K, Kodilkar J, Danve N, Subramanian I, Katoh M, Shimizu-Yoshida Y, Ghosh S, Jere A, Kitano H.:
    “Network analyses based on comprehensive molecular interaction maps reveal robust control structures in yeast stress response pathways.”
    NPJ Syst Biol Appl 2, 15018 (2016)
  • 3.Seita J, Sahoo D, Rossi DJ, Battacharya D, Serwold T, Inlay MA, Ehrlich LIR, Fathman JW, Dill DL, Weissman IL.:
    “Gene Expression Commons: an open platform for absolute gene expression profiling.”
    PLoS ONE 2012;7(7)

Related Links

Lab Members

Principal investigator

Kazuhiro Sakurada
Group Director

Core members

Eiryo Kawakami
Senior Scientist
Jun Seita
Senior Scientist
Ichiro Miki
Research Scientist

Contact Information

East building E216,
1-7-22 Suehiro-cho, Tsurumi-ku,
Yokohama City, Kanagawa,
230-0045, Japan
Tel: +81-(0)45-503-9691
Fax: +81-(0)45-503-9278
Email: kazuhiro.sakurada [at] riken.jp