研究概要

主要論文

• 1.Mandai M, et al;
  "Autologous Induced Stem-Cell-Derived Retinal Cells for Macular Degeneration"
  N. Engl. J. Med 376(11):1038-1046 (2017)
• 2.Mandai M, et al;
  "iPSC-derived retina transplants improve vision in rd1 end-stage retinal degeneration mice"
  Stem Cell Reports 8,69–83 (2017)
• 3.Sugita S, et al;
  "Successful transplantation of retinal pigment epithelial cells from MHC homozygote iPS cells in MHC-matched models"
  Stem Cell Reports 7(4):635-648 (2016)
• 4.Sugita S, et al;
  "Lack of T-cell response to iPS cell-derived retinal pigment epithelial cells from HLA homozygous donors"
  Stem Cell Reports 7(4):619-634 (2016)
• 5.Shirai H, et al.:
  "Transplantation of human embryonic stem cell-derived retinal tissue in two primate models of retinal degeneration."
  PNAS U S A pii: 201512590. (2015)
• 6.Assawachananont J, et al.:
  "Transplantation of Embryonic and Induced Pluripotent Stem Cell-Derived 3D Retinal Sheets into Retinal Degenerative Mice."
  Stem Cell Reports 2.662-74 (2014)
• 7.Kamao H, et al.:
  "Characterization of human induced pluripotent stem cell-derived retinal pigment epithelium cell sheets aiming for clinical application."
  Stem Cell Reports 2.205-18 (2014)
• 8.Jin Z. B, et al.:
  "Modeling retinal degeneration using patient-specific induced pluripotent stem cells."
  PLoS One 6.e17084 (2011)
• 9.Osakada F, et al.
  "Toward the generation of rod and cone photoreceptors from mouse, monkey and human embryonic stem cells."
  Nat Biotechnol 26.215-24 (2008)
• 10.Osakada F, et al.:
  "Wnt signaling promotes regeneration in the retina of adult mammals."
  J Neurosci 27.4210-9 (2007)

研究成果（プレスリリース）

• 

  2020年11月5日
  iPS細胞でヒト心臓の機能を知る

• 

  2019年8月9日
  胚盤胞の分化を再現

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