研究概要

主要論文

• 1. Nagata R., Akama Y., Goncalves P., Serafini N., Kageyama T., Sato M, Shimaoka M., Ohno H. and Satoh-Takayama N.*
  "Acute peritonitis-induced adipose CD127+ ILC1s express PD-L1 and ameliorate inflammation in mice."
  Nature Communication, 17(1):2391, 2026.
• 2. Satoh-Takayama N.*, Shigeno Y., Nagata R., Kato T., Nakanishi Y., Kageyama T., Tachibana N., Ito A., Benno Y., and Ohno H.
  "Fibroblasts sense commensal-derived metabolites and regulate innate IL-13-dependent immunity in the stomach."
  Mucosal Immunology, 19(2):1862-1874, 2026.
• 3. Ogawa C., Zou C., Paucar Iza YA., Park T., Harada J. Satoh-Takayama N., Kuroda M., Brown CC. and Taniuchi I.
  "Runx-CBFb regulates the development of tolerogenic Thetis cells."
  Nature Immunology, 27(8):1633-1642, 2026
• 4. Akama Y., Park EJ., Satoh-Takayama N., Ito A., Kawamoto E., Gaowa A., Matsuno E., Oikawa S., Saito M., Inoue T., Suzuki K., and Shimaoka M.
  "Roles of programmed death-1 and muscle innate lymphoid -derived IL-13 in sepsis-induced intensive care unit-acquired weakness."
  Journal of Cachexia, Sarcopenia and Muscle. 15(5):1999-2012, 2024.
• 5. Tsugawa H., Ishihara T., Ogasa K., Iwanami S., Hori A., Takahashi M., Yamada Y., Satoh-Takayama N., Ohno H., Minoda A., and Arita M.
  "A lipidome landscape of aging in mice."
  Nature Aging, 4(5):709-726, 2024.
• 6. Ito A., Akama Y., Satoh-Takayama N., Saito K., Kato T., Kawamoto E., Gaowa A., Park EJ., Takao M., Shimaoka M.
  "Possible metastatic stage-dependent ILC2 activation induces differential function of MDSCs through IL-13/IL-13Ra1 signaling during the progression of breast cancer lung metastasis."
  Cancers. 14(13): 3267, 2022.
• 7. Shi Z., Takeuchi T., Nakanishi Y., Kato T., Beck K., Nagata R., Kageyama T., Ito A., Ohno H. and. Satoh-Takayama N.*
  "A Japanese Herbal formula, Daikenchuto, alleviates experimental colitis by reshaping microbial profiling and enhancing group 3 innate lymphoid cells."
  Frontiers in Immunology. 13: 903459, 2022.
• 8. Akama Y., Park EJ., Satoh-Takayama N., Gaowa A., Ito A., Kawamoto E., Darkwas S., Appiah M.G., Myint PK., Ohno H., Imai H. and Shimaoka M.
  "Sepsis induces deregulation of IL-13 production and PD-1 expression in lung group 2 innate lymphoid cells."
  Shock. 55: 357-370, 2021.
• 9. Satoh-Takayama N.*, Kato T., Motomura Y., Kageyama T., Taguchi-Atarashi N., Daitoku-Kinoshita R., Kuroda E., Di Santo JP., Mimuro H., Moro K. and Ohno H.
  "Bacteria-induced group 2 innate lymphoid cells in the stomach provide immune protection through induction of IgA."
  Immunity. 52: 635-649, 2020.
• 10. Tamaura M., Satoh-Takayama N., Tsumura M., Kageyama T., Hayakawa S., Asano T., Goda S., Nakayama M., Koseki H., Ohara O., Okada S., Ohno. H. and Kobayashi M.
  "Human gain-of-function STAT1 mutation disturbs IL-17 immunity in mice."
  International Immunology. 32: 259-272, 2020.

研究成果（プレスリリース）

• 

  2026年2月18日
  胃の共生細菌がピロリ菌感染から胃を守る仕組みを解明

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