Centers & Labs

RIKEN Center for Sustainable Resource Science

Cell Function Research Team

Team Leader: Keiko Sugimoto (Ph.D.)
Keiko  Sugimoto(Ph.D.)

We investigate how plants integrate developmental and environmental cues to maximise organ growth under the changing environment. We also explore how plants establish and maintain cellular differentiation status and how various stress stimuli override the developmental commitments to undergo cellular reprogramming. These strategies should allow us identify key modulators of organ growth and reprogramming, thus providing molecular basis for crop improvement.

Main Research Field

Biology

Related Research Fields

Agricultural sciences

Research Subjects

  • Molecular dissection of plant organ growth
  • Molecular dissection of cellular reprogramming in plants
  • Genetic manipulation of cellular differentiation in crops

Selected Publications

  1. Ikeuchi M, Iwase A, Rymen B, H Harashima H, Shibata M, Ohnuma M, Breuer C, Morao AK, de Lucas M, De Veylder L, Goodrich J, Brady SM, Roudier F, and Sugimoto K.:
    "PRC2 represses dedifferentiation of mature somatic cells in Arabidopsis"
    Nature Plants 15089 (2015)
  2. Kumar N, Harashima H, Kalve S, Bramsiepe J, Wang K, Sizani BL, Bertrand LL, Johnson MC, Faulk C, Dale R, Simmons LA, Churchman ML, Sugimoto K, Kato N, Dasanayake M, Beemster G, Schnittger A, Larkin JC.:
    "Functional conservation in the SIAMESE-RELATED family of Cyclin-dependent kinase inhibitors in land plants"
    Plant Cell 27: 3065-3080 (2015)
  3. Iwase A, Mita K, Nonaka S, Ikeuchi M, Koizuka K, Ohnuma M, Ezura H, Imamura J, Sugimoto K.:
    "WIND1-based acquisition of regeneration competency in Arabidopsis and rapeseed"
    J Plant Res 128(3):389-97 (2015)
  4. Iwase A, Mitsuda N, Ikeuchi M, Ohnuma M, Koizuka C, Kawamoto K, Imamura J, Ezura H, Sugimoto K.:
    "Arabidopsis WIND1 induces callus formation in rapeseed, tomato and tobacco"
    Plant Signal & Behav 8(12): e27432 (2014)
  5. Breuer C, Morohashi K, Kawamura A, Takahashi N. Ishida T, Umeda M, Grotewold E, and Sugimoto K.:
    "Transcriptional repression of the APC/C activator CCS52A1 promotes the active termination of cell growth"
    EMBO J 31, 4488-4801 (2012)
  6. Schneider K, Breuer C, Kawamura A, Jikumaru Y, Hanada A, Fujioka S, Ichikawa T, Kondou Y, Minami M, Kamiya Y, Yamaguchi S, and Sugimoto K.:
    "Arabidopsis PIZZA has the capacity to acylate brassinosteroids"
    PLoS ONE 7(10):e46805 (2012)
  7. Ishida T, Yoshimura M, Miura K, and Sugimoto K.:
    "MMS21/HPY2 and SIZ1, two Arabidopsis SUMO E3 ligases, have distinct functions in development"
    PLoS ONE 7(10):e46897 (2012)
  8. Iwase A, Mitsuda N, Koyama T, Hiratsu K, Kojima M, Arai T, Inoue Y, Seki M, Sakakibara H, Sugimoto K and Ohme-Takagi M.:
    "The AP2/ERF transcription factor WIND1 controls cell dedifferentiation in Arabidopsis"
    Curr Biol 21(6): 508-514 (2011)
  9. Ishida, T., Adachi, S., Yoshimura, M., Shimizu, K., Umeda, M. and Sugimoto, K.:
    "Auxin modulates the transition from the mitotic cycle to the endocycle in Arabidopsis"
    Development 137: 63-71 (2010)
  10. Breuer C, Kawamura A, Ichikawa T, Tominaga-Wada R, Wada T, Kondou Y, Muto Y, Matsui M, and Sugimoto K.:
    "The trihelix transcription factor AtGTL1 controls ploidy-dependent cell growth in the Arabidopsis trichome"
    Plant Cell 21: 2307-2322 (2009)

Lab Members

Principal Investigator

Keiko Sugimoto
Team Leader

Core Members

Akira Iwase
Research Scientist
Hirofumi Harashima
Research Scientist
Momoko Ikeuchi
Special Postdoctoral Researcher
Bart Rymen
Postdoctoral Researcher
Michitaro Shibata
Visiting Researcher
Anna Franciosini
Visiting Researcher
Ayako Kawamura
Technical Staff II

Contact information

E612 East Research Building 1-7-22 Suehiro-cho, Tsurumi-ku, Yokohama City, Kanagawa, 230-0045, Japan
Tel: +81-(0)45-503-9575
Fax: +81-(0)45-503-9591

Email: keiko.sugimoto [at] riken.jp

Recent research results

March 17, 2017: RIKEN RESEARCH
How plants shoot back