Centers & Labs

RIKEN Center for Sustainable Resource Science

Cell Function Research Team

Team Leader: Keiko Sugimoto (Ph.D.)
Keiko  Sugimoto(Ph.D.)

We investigate how plants integrate developmental and environmental cues to maximise organ growth under the changing environment. We also explore how plants establish and maintain cellular differentiation status and how various stress stimuli override the developmental commitments to undergo cellular reprogramming. These strategies should allow us identify key modulators of organ growth and reprogramming, thus providing molecular basis for crop improvement.

Main Research Field

Biology

Related Research Fields

Agricultural sciences

Keywords

  • Cell proliferation
  • Cell differentiation
  • Cell dedifferentiation
  • totipotency
  • regeneration

Selected Publications

  1. Iwase A, Harashima H, Ikeuchi M, Rymen B, Ohnuma M, Komaki S, Morohashi K, Kurata T, Nakata M, Ohme-Takagi M, Grotewold E, Sugimoto K.:
    "WIND1 promotes shoot regeneration through transcriptional activation of ESR1 in Arabidopsis"
    Plant Cell 29(1): 54-69 (2017)
  2. Rymen B, Kawamura A, Schäfer S, Breuer C, Iwase A, Shibata M, Ikeda M, Mitsuda N, Koncz C, Ohme-Takagi M, Matsui M, Sugimoto K.:
    "ABA suppresses root hair growth via the OBP4 transcriptional regulator"
    Plant Physiol 173(3): 1750-1762 (2017)
  3. Ikeuchi M, Iwase A, Rymen B, H Harashima H, Shibata M, Ohnuma M, Breuer C, Morao AK, de Lucas M, De Veylder L, Goodrich J, Brady SM, Roudier F, and Sugimoto K.:
    "PRC2 represses dedifferentiation of mature somatic cells in Arabidopsis"
    Nature Plants 15089 (2015)
  4. Kumar N, Harashima H, Kalve S, Bramsiepe J, Wang K, Sizani BL, Bertrand LL, Johnson MC, Faulk C, Dale R, Simmons LA, Churchman ML, Sugimoto K, Kato N, Dasanayake M, Beemster G, Schnittger A, Larkin JC.:
    "Functional conservation in the SIAMESE-RELATED family of Cyclin-dependent kinase inhibitors in land plants"
    Plant Cell 27: 3065-3080 (2015)
  5. Iwase A, Mita K, Nonaka S, Ikeuchi M, Koizuka K, Ohnuma M, Ezura H, Imamura J, Sugimoto K.:
    "WIND1-based acquisition of regeneration competency in Arabidopsis and rapeseed"
    J Plant Res 128(3):389-97 (2015)
  6. Iwase A, Mitsuda N, Ikeuchi M, Ohnuma M, Koizuka C, Kawamoto K, Imamura J, Ezura H, Sugimoto K.:
    "Arabidopsis WIND1 induces callus formation in rapeseed, tomato and tobacco"
    Plant Signal & Behav 8(12): e27432 (2014)
  7. Breuer C, Morohashi K, Kawamura A, Takahashi N. Ishida T, Umeda M, Grotewold E, and Sugimoto K.:
    "Transcriptional repression of the APC/C activator CCS52A1 promotes the active termination of cell growth"
    EMBO J 31, 4488-4801 (2012)
  8. Iwase A, Mitsuda N, Koyama T, Hiratsu K, Kojima M, Arai T, Inoue Y, Seki M, Sakakibara H, Sugimoto K and Ohme-Takagi M.:
    "The AP2/ERF transcription factor WIND1 controls cell dedifferentiation in Arabidopsis"
    Curr Biol 21(6): 508-514 (2011)
  9. Ishida, T., Adachi, S., Yoshimura, M., Shimizu, K., Umeda, M. and Sugimoto, K.:
    "Auxin modulates the transition from the mitotic cycle to the endocycle in Arabidopsis"
    Development 137: 63-71 (2010)
  10. Breuer C, Kawamura A, Ichikawa T, Tominaga-Wada R, Wada T, Kondou Y, Muto Y, Matsui M, and Sugimoto K.:
    "The trihelix transcription factor AtGTL1 controls ploidy-dependent cell growth in the Arabidopsis trichome"
    Plant Cell 21: 2307-2322 (2009)

Lab Members

Principal Investigator

Keiko Sugimoto
Team Leader

Core Members

Akira Iwase
Research Scientist
Bart Rymen
Research Scientist
David Seth Favero
Postdoctoral Researcher
Momoko Ikeuchi
Visiting Researcher
Michitaro Shibata
Visiting Researcher
Ayako Kawamura
Technical Staff II

Contact information

E612 East Research Building 1-7-22 Suehiro-cho, Tsurumi-ku, Yokohama City, Kanagawa, 230-0045, Japan
Tel: +81-(0)45-503-9575
Fax: +81-(0)45-503-9591

Email: keiko.sugimoto [at] riken.jp

Related links

Recent research results

March 17, 2017: RIKEN RESEARCH
How plants shoot back