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RIKEN Center for Advanced Intelligence Project Data-Driven Experimental Design Team

Team Director: Ichiro Takeuchi (D.Eng.)

Research Summary

Ichiro  Takeuchi(D.Eng.)

In various fields of scientific research, data-driven approaches are enabling the generation of hypotheses, the planning of experiments, and even the discovery of new knowledge, thereby bringing innovation to the research process. At the same time, data-driven research faces challenges such as limited interpretability, susceptibility to bias, and a lack of reproducibility, making it essential to ensure reliability and transparency. In conventional research, systematic practices based on "experimental design" have been established as methodologies for research design—determining which experiments to conduct and how to draw conclusions from their results. The mission of our team is to evolve and advance this framework to adapt to data-driven research, thereby establishing a foundation for "data-driven experimental design," and ensuring the sound development of data-driven science. To achieve this goal, we are developing novel machine learning techniques tailored to scientific research and demonstrating their effectiveness across a range of scientific challenges.

Main Research Fields

  • Computer Science

Related Research Fields

  • Materials Sciences
  • Biology & Biochemistry
  • Molecular Biology & Genetics
  • Clinical Medicine
  • Mathematics

Research Subjects

  • Data Science

Selected Publications

  • 1. Shiraishi T., Miwa D., Katsuoka T., Duy V.N.L., Taji K., Takeuchi I.:
    "Statistical Test for Attention Maps in Vision Transformers"
    International Conference on Machine Learning (2024)
  • 2. Duy V.N.L., Lin H.T., Takeuchi I.:
    "CAD-DA: Controllable Anomaly Detection after Domain Adaptation by Statistical Inference"
    AI&Statistics (2024)
  • 3. Goto K., Tamehiro N., Yoshida T., Hanada H., Sakuma T., Adachi R., Kondo K., Takeuchi I.:
    "Novel Machine Learning Method AllerStat Identifies Statistically Significant Allergen-Specific Patterns in Protein Sequences."
    Journal of Biological Chemistry. Vol.299-6, 104733 (2023)
  • 4. Hashimoto N., Takagi Y., Masuda H., Miyoshi H., Kohno K., Nagaishi M., Sato K., Takeuchi M., Furuta T., Kawamoto K., Yamada K., Moritsubo M., Inoue K., Shimasaki Y., Ogura Y., Imamoto T., Mishina T., Tanaka K., Kawaguchi Y., Nakamura S., Ohshima K., Hontani H., Takeuchi I.:
    "Case-based Similar Image Retrieval for Weakly Annotated Large Histopathological Images of Malignant Lymphoma Using Deep Metric Learning."
    Medical Image Analysis. Vol.85 (2023)
  • 5. Kato H., Hanada H., Takeuchi I.:
    "Safe RuleFit: Learning Optimal Sparse Rule Model by Meta Safe Screening."
    IEEE Transactions on Pattern Analysis and Machine Intelligence. Vol.45-2, pp.2330-2343 (2023)
  • 6. Miwa D., Duy V.N.L., Takeuchi I.:
    "Valid P-Value for Deep Learning-driven Salient Region"
    The International Conference on Learning Representation (2023)
  • 7. Ndiaye E., Takeuchi I.:
    "Root-finding Approaches for Computing Conformal Prediction Set"
    Machine Learning (2022)
  • 8. Duy V.N.L., Takeuchi I.:
    "More Powerful Conditional Selective Inference for Generalized Lasso by Parametric Programming."
    Journal of Machine Learning Research. Vol.23(300) (2022)
  • 9. Duy V.N.L., Iwazaki S., Takeuchi I.:
    "Quantifying Statistical Significance of Neural Network-based Image Segmentation by Selective Inference."
    Neural Information Processing Systems (2022)
  • 10. Inatsu Y., Takeno S., Karasuyama M., Takeuchi I.:
    "Bayesian Optimization for Distributionally Robust Chance-constrained Problem."
    International Conference on Machine Learning (2022)

Related Links

Lab Members

Principal investigator

Ichiro Takeuchi
Team Director

Core members

Noriaki Hashimoto
Research Scientist
Toru Ujihara
Visiting Scientist
Keiichi Inoue
Visiting Scientist
Vo Nguyen Le Duy
Visiting Scientist
Kentaro Kutsukake
Visiting Scientist
Hiroyuki Hanada
Visiting Scientist
Shuichi Nishino
Junior Research Associate
Tomohiro Shiraishi
Junior Research Associate
Xudong Chen
Research Part-time Worker I
Onur Boyar
Research Part-time Worker I

Contact Information

#427 4th Floor Bldg. 2, Nagoya University, Furo-cho, Chikusa-ku,
Nagoya, Aichi,
464-8603, Japan
Email: ichiro.takeuchi@riken.jp

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