RIKEN Center for Integrative Medical Sciences (IMS)
Director: Kazuhiko Yamamoto (M.D., Ph.D.)
At the Center for Integrative Medical Sciences, we aim to elucidate the pathogenesis of human diseases and establish new therapeutic methodologies by conducting cutting-edge research on human genome and immune functions. To that end, we have established four divisions: (1) Division of Genomic Medicine, (2) Division of Human Immunology, (3) Division of Disease Systems Biology, and (4) Division of Cancer Immunology. These groups work together to promote state-of-the-art research.
We apply multi-omics analyses across the hierarchy of genome, gene expressions, proteins, lipids, cells, tissues, and individuals by utilizing computational methods of data analysis, combining statistics and AI technology. We also have established a platform that will allow us to better understand the results obtained in experimental animals and apply them to human immunology research, and to elucidate mechanisms of human pathology using experimental systems such as cell and animal models. Further, we are utilizing these infrastructures to develop next generation research.
Organization
- Laboratory for Transcriptome Technology
- Piero Carninci (Ph.D.)
- Laboratory for Cellular Function Conversion Technology
- Harukazu Suzuki (Ph.D.)
- Laboratory for Applied Computational Genomics
- Michiel Jan Laurens De Hoon (Ph.D.)
- Laboratory for Large-Scale Biomedical Data Technology
- Takeya Kasukawa (Ph.D.)
- Laboratory for Advanced Genomics Circuit
- Jay W. Shin (D.Sc.)
- Laboratory for Comprehensive Genomic Analysis
- Yasushi Okazaki (M.D., Ph.D.)
- RIKEN-IFOM Joint Laboratory for Cancer Genomics
- Yasuhiro Murakawa (M.D., Ph.D)
- Laboratory for Genotyping Development
- Yukihide Momozawa (D.V.M., Ph.D.)
- Laboratory for Statistical and Translational Genetics
- Chikashi Terao (M.D., Ph.D)
- Laboratory for Pharmacogenomics
- Taisei Mushiroda (Ph.D.)
- Laboratory for Cardiovascular Genomics and Informatics
- Kaoru Ito (M.D., Ph.D)
- Laboratory for Systems Genetics
- Yukinori Okada (M.D., Ph.D.)
- Laboratory for Functional Non-coding Genomics
- Yuka Iwasaki (Ph.D.)
- Laboratory for Retrotransposon Dynamics
- Tomoichiro Miyoshi (Ph.D.)
- Laboratory for Regulatory Genomics
- Chung Chau Hon (Ph.D.)
- Laboratory for Autoimmune Diseases
- Kazuhiko Yamamoto (M.D., Ph.D)
- Laboratory for Human Immunogenetics
- Kazuyoshi Ishigaki (M.D., Ph.D.)
- Laboratory for Lymphocyte Differentiation
- Tomohiro Kurosaki (M.D., Ph.D)
- Laboratory for Transcriptional Regulation
- Ichiro Taniuchi (M.D., Ph.D)
- Laboratory for Immune Cell Systems
- Shigeo Koyasu (D.Sc.)
- Laboratory for Innate Immune Systems
- Kazuyo Moro (Ph.D.)
- Laboratory for Immune Homeostasis
- Taishin Akiyama (Ph.D.)
- Laboratory for Cytokine Regulation
- Masato Kubo (Ph.D.)
- Laboratory for Immunological Memory
- Shiki Takamura (D.V.M., Ph.D.)
- Laboratory for Inflammatory Immune Metabolism
- Sonia Sharma (Ph.D.)
- Laboratory for Infectious Diseases and Immunology
- Kosuke Miyauchi (Ph.D.)
- Laboratory for Developmental Genetics
- Haruhiko Koseki (M.D., Ph.D)
- Laboratory for Intestinal Ecosystem
- Hiroshi Ohno (M.D., Ph.D)
- Laboratory for Integrative Genomics
- Jun Seita (M.D., Ph.D.)
- Laboratory for Mucosal Immunity
- Sidonia Fagarasan (M.D., Ph.D)
- Laboratory for Gut Homeostasis
- Kenya Honda (M.D., Ph.D)
- Laboratory for Skin Homeostasis
- Masayuki Amagai (M.D., Ph.D)
- Laboratory for Tissue Dynamics
- Takaharu Okada (Ph.D.)
- Laboratory for Integrated Cellular Systems
- Katsuyuki Yugi (Ph.D.)
- Laboratory for Metabolomics
- Makoto Arita (Ph.D.)
- Laboratory for Metabolic Networks
- Toshimori Kitami (Ph.D.)
- Laboratory for Epigenome Inheritance
- Azusa Inoue (Ph.D.)
- Laboratory for Symbiotic Microbiome Sciences
- Wataru Suda (D.Agr.)
- Laboratory for Medical Science Mathematics
- Tatsuhiko Tsunoda (Ph.D., Ph.D.)
- Laboratory for Cancer Genomics
- Hidewaki Nakagawa (M.D., Ph.D)
- Laboratory for Immunotherapy
- Shin-ichiro Fujii (M.D., Ph.D)
- Laboratory for Human Disease Models
- Fumihiko Ishikawa (M.D., Ph.D)
- Laboratory for Cancer Invasion and Metastasis
- Kohei Miyazono (M.D., Ph.D)
- Laboratory for Biomedical Ethics and Co‐design
- Muto Kaori (Ph.D.)
- Epigenome Dynamics RIKEN ECL Research Team
- Shihori Yokobayashi (Ph.D.)
- Young Chief Investigator Program
- Hiroshi Ohno (M.D., Ph.D.)
-
- Proteome Homeostasis Research Unit
- Koshi Imami (Ph.D.)
- Precision Immune Regulation RIKEN ECL Research Unit
- Naoko Satoh-Takayama (Ph.D.)
- Drug Discovery Antibody Platform Unit
- Kazuhiko Yamamoto (M.D., Ph.D.)
- aAVC Drug Translational Unit
- Shin-ichiro Fujii (M.D., Ph.D)
Recent Research Results
Jun. 5, 2024
Cracking the aging code: Insights into lipid changes
Mar. 15, 2024
Gut bacteria important for overcoming milk allergy
Jan. 19, 2024
Hot on the tracks of extracellular vesicles
Events
Publications
Related Links
Contact Information
1-7-22 Suehiro-cho, Tsurumi-ku,
Yokohama, Kanagawa
230-0045, Japan
Email: ims-web [at] riken.jp