Research Summary

Selected Publications

Papers with an asterisk(*) are based on research conducted outside of RIKEN.

• 1.Yokouchi M, Atsugi T, Logtestijn MV, Tanaka RJ, Kajimura M, Suematsu M, Furuse M, Amagai M, Kubo A.:
  "Epidermal cell turnover across tight junctions based on Kelvin's tetrakaidecahedron cell shape."
  eLife 5:e19593. (2016).
• 2.Kobayashi T, Glatz M, Horiuchi K, Kawasaki H, Akiyama H, Kaplan DH, Kong HH, Amagai M, Nagao K.:
  "Dysbiosis and Staphylococcus aureus colonization drives inflammation in atopic dermatitis."
  Immunity 42, 756-66. (2015).
• 3.Matsui T and Amagai M.:
  "Dissecting the formation, structure and barrier function of the stratum corneum."
  Int. Immunol. 27: 269-80, (2015).
• 4.Sasaki T, Shiohama A, Kubo A, Kawasaki H, Ishida-Yamamoto A, Yamada T, Hachiya T, Shimizu A, Okano H, Kudoh J, Amagai M.:
  "A homozygous nonsense mutation in the gene for Tmem79, a component for the lamellar granule secretory system, produces spontaneous eczema in an experimental model of atopic dermatitis."
  J Allergy Clin Immunol 132 (5): 1111-1120 e1114, 2013
• 5.*Kawasaki H, Nagao K, Kubo A, Hata T, Shimizu A, Mizuno H, Yamada T, Amagai M.:
  "Altered stratum corneum barrier and enhanced percutaneous immune responses in filaggrin-null mice."
  J Allergy Clin Immunol, 129 (6): 1538-1546, 2012
• 6.*Kubo A, Nagao K, Amagai M.:
  "Epidermal barrier dysfunction and cutaneous sensitization in atopic diseases."
  J Clin Invest 122 (2), 440-447, 2012
• 7.*Kubo A, Nagao K, Yokouchi M, Sasaki H, Amagai M.:
  "External antigen uptake by Langerhans cells with reorganization of epidermal tight junction barriers."
  J Exp Med 206 (13):2937-2946, 2009
• 8.*Stanley J R and Amagai M.:
  "Pemphigus, bullous impetigo, and the staphylococcal scalded-skin syndrome."
  N Eng J Med 355: 1800-1810, 2006
• 9.*Amagai M, Matsuyoshi N, Wang ZH, Andl C, Stanley JR.:
  "Toxin in bullous impetigo and staphylococcal scalded skin syndrome targets desmoglein 1."
  Nature Medicine 6: 1275-1277, 2000
• 10.*Amagai M, Tsunoda K, Suzuki H, Nishifuji K, Koyasu S, Nishikawa T.:
  "Use of autoantigen knockout mice to develop an active autoimmune disease model of pemphigus."
  J Clin Invest 105: 625-631, 2000

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