RIKEN BioResource Research Center (BRC®) Integrated Bioresource Information Division
Division Director: Hiroshi Masuya (Ph.D.)
Research Summary

As it is exactly said “No data, No resource”, “Information” is an essential element of bioresources as the basic infrastructure for promotion of the life science. Integrated Bioresource Information Division develops information technology that describes and integrates bioresources related information including genome, phenotype and its utilization in scientific studies. The Division also aims and facilitate wide, effective and efficient use of bioresources for R&D in science and industry by analyses of bioresource-related big data and operation of the Website.
Main Research Fields
- Informatics
Related Research Fields
- Complex Systems
- Humanities
- Interdisciplinary Science & Engineering
- Mathematical & Physical Sciences
- Engineering
- Biological Sciences
- Biology
- Agricultural Sciences
- Medicine, Dentistry & Pharmacy
- Intelligent informatics
- Life & Health & Medical informatics
- Mathematical informatics
Keywords
- Data integration
- Ontology
- Semantic Web
- Mathematical informatics
- Statistical analysis
Selected Publications
- 1.
Kadoya T, Suzuki K, and Terui A
"Linking energetic instability to compositional changes in biological communities"
PNAS in press (2025) - 2.
Nobusada T, Yip CW, Agrawal S, Severin J, Abugessaisa I, Hasegawa A, Hon CC, Ide S, Koido M, Kondo A, Masuya H, Oki S, Tagami M, Takada T, Terao C, Thalhath N, Walker S, Yasuzawa K, Shin JW, De Hoon MJL, Carninci P, Kawaji H, and Kasukawa T
"Update of the FANTOM web resource: enhancement for studying noncoding genomes"
Nucleic acids research, 53(D1), D419–D424. (2025)
doi: 10.1093/nar/gkae1047 - 3.
Kyoda, K., Itoga, H., Yamagata, Y., Fujisawa, E., Wang, F., Miranda-Miranda, M., Yamamoto, H., Nakano, Y., Tohsato, Y., & Onami, S
"SSBD: an ecosystem for enhanced sharing and reuse of bioimaging data"
Nucleic acids research, 53(D1), D1716–D1723. (2025)
doi:10.1093/nar/gkae860 - 4.
Yamagata Y, Kushida T, Onami S and Masuya H
"Homeostasis imbalance process ontology: a study on COVID-19 infectious processes."
BMC Medical Informatics and Decision Making, 23 Supplement 4, (2024)
doi: 10.1186/s12911-024-02516-0 - 5.
Yamagata Y, Fukuyama T, Onami S and Masuya H
"Prototyping an Ontological Framework for Cellular Senescence Mechanisms: A Homeostasis Imbalance Perspective."
Scientific Data, 11, Article number: 485, (2024)
doi: 10.1038/s41597-024-03331-y - 6.
Kumaishi K, Usui E, Suzuki K, Kobori S, Sato T, Toda Y, Takanashi H, Shinozaki S, Noda M, Takakura A, Matsumoto K, Yamasaki Y, Tsujimoto H, Iwata H, Ichihashi Y
"High throughput method of 16S rRNA gene sequencing library preparation for plant root microbial community profiling"
Scientific Reports, 12(1), 1-10, (2022).
doi:10.1038/s41598-022-23943-x - 7.
Suzuki K, Matsuzaki SS, Masuya H
"Decomposing predictability to identify dominant causal drivers in complex ecosystems"
PNAS, 119 (42) e220440511 (2022)
doi:10.1073/pnas.2204405119 - 8.
Takada T, Fukuta K, Usuda D, Kushida T, Kondo S, Kawamoto S, Yoshiki A, Obata Y, Fujiyama A, Toyoda A, Noguchi H, Shiroishi T, Masuya H
"MoG+: a database of genomic variations across three mouse subspecies for biomedical research., Mammalian Genome"
Mammalian Genome. 33, 31-43 (2021)
doi:10.1007/s00335-021-09933-w - 9.
Suzuki K, Nakaoka S, Fukuda S, Masuya H
"Energy landscape analysis elucidates the multistability of ecological communities across environmental gradients"
Ecological Monographs. (2021) - 10.
Masuya H, Usuda D, Nakata H, Yuhara N, Kurihara K, Namiki Y, Iwase S, Takada T, Tanaka N, Suzuki K, Yamagata Y, Kobayashi N, Yoshiki A, Kushida T
"Establishment and application of information resource of mutant mice in RIKEN BioResource Research Center"
Laboratory Animal Research. 37(6), (2021)
Related Links
Lab Members
Principal investigator
- Hiroshi Masuya
- Division Director
Core members
- Shigeru Iwase
- Senior Research Scientist
- Tatsuya Kushida
- Research Scientist
- Kenta Suzuki
- Research Scientist
- Yuki Yamagata
- Research Scientist
- Toyoyuki Takada
- Research & Development Scientist
- Sotaro Takano
- Research & Development Scientist
- Norio Kobayashi
- Research & Development Scientist
- Naomi Yuhara
- Technical Staff II
- Keiko Kurihara
- Technical Staff II
- Daiki Usuda
- Technical Staff II
- Yuri Namiki
- Technical Staff II
Contact Information
Room 113, Information and JCM Building,
3-1-1 Koyadai,
Tsukuba, Ibaraki,
305-0074 Japan
Tel: +81-(0)29-829-9112
Fax: +81-(0)29-836-9337
Email: hiroshi.masuya@riken.jp