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RIKEN BioResource Research Center (BRC®) Integrated Bioresource Information Division

Division Director: Hiroshi Masuya (Ph.D.)

Research Summary

Hiroshi  Masuya(Ph.D.)

As it is exactly said “No data, No resource”, “Information” is an essential element of bioresources as the basic infrastructure for promotion of the life science. Integrated Bioresource Information Division develops information technology that describes and integrates bioresources related information including genome, phenotype and its utilization in scientific studies. The Division also aims and facilitate wide, effective and efficient use of bioresources for R&D in science and industry by analyses of bioresource-related big data and operation of the Website.

Main Research Fields

  • Informatics

Related Research Fields

  • Complex Systems
  • Humanities
  • Interdisciplinary Science & Engineering
  • Mathematical & Physical Sciences
  • Engineering
  • Biological Sciences
  • Biology
  • Agricultural Sciences
  • Medicine, Dentistry & Pharmacy
  • Intelligent informatics
  • Life & Health & Medical informatics
  • Mathematical informatics

Keywords

  • Data integration
  • Ontology
  • Semantic Web
  • Mathematical informatics
  • Statistical analysis

Selected Publications

  • 1. Kadoya T, Suzuki K, and Terui A
    "Linking energetic instability to compositional changes in biological communities"
    PNAS in press (2025)
  • 2. Nobusada T, Yip CW, Agrawal S, Severin J, Abugessaisa I, Hasegawa A, Hon CC, Ide S, Koido M, Kondo A, Masuya H, Oki S, Tagami M, Takada T, Terao C, Thalhath N, Walker S, Yasuzawa K, Shin JW, De Hoon MJL, Carninci P, Kawaji H, and Kasukawa T
    "Update of the FANTOM web resource: enhancement for studying noncoding genomes"
    Nucleic acids research, 53(D1), D419–D424. (2025)
    doi: 10.1093/nar/gkae1047
  • 3. Kyoda, K., Itoga, H., Yamagata, Y., Fujisawa, E., Wang, F., Miranda-Miranda, M., Yamamoto, H., Nakano, Y., Tohsato, Y., & Onami, S
    "SSBD: an ecosystem for enhanced sharing and reuse of bioimaging data"
    Nucleic acids research, 53(D1), D1716–D1723. (2025)
    doi:10.1093/nar/gkae860
  • 4. Yamagata Y, Kushida T, Onami S and Masuya H
    "Homeostasis imbalance process ontology: a study on COVID-19 infectious processes."
    BMC Medical Informatics and Decision Making, 23 Supplement 4, (2024)
    doi: 10.1186/s12911-024-02516-0
  • 5. Yamagata Y, Fukuyama T, Onami S and Masuya H
    "Prototyping an Ontological Framework for Cellular Senescence Mechanisms: A Homeostasis Imbalance Perspective."
    Scientific Data, 11, Article number: 485, (2024)
    doi: 10.1038/s41597-024-03331-y
  • 6. Kumaishi K, Usui E, Suzuki K, Kobori S, Sato T, Toda Y, Takanashi H, Shinozaki S, Noda M, Takakura A, Matsumoto K, Yamasaki Y, Tsujimoto H, Iwata H, Ichihashi Y
    "High throughput method of 16S rRNA gene sequencing library preparation for plant root microbial community profiling"
    Scientific Reports, 12(1), 1-10, (2022).
    doi:10.1038/s41598-022-23943-x
  • 7. Suzuki K, Matsuzaki SS, Masuya H
    "Decomposing predictability to identify dominant causal drivers in complex ecosystems"
    PNAS, 119 (42) e220440511 (2022)
    doi:10.1073/pnas.2204405119
  • 8. Takada T, Fukuta K, Usuda D, Kushida T, Kondo S, Kawamoto S, Yoshiki A, Obata Y, Fujiyama A, Toyoda A, Noguchi H, Shiroishi T, Masuya H
    "MoG+: a database of genomic variations across three mouse subspecies for biomedical research., Mammalian Genome"
    Mammalian Genome. 33, 31-43 (2021)
    doi:10.1007/s00335-021-09933-w
  • 9. Suzuki K, Nakaoka S, Fukuda S, Masuya H
    "Energy landscape analysis elucidates the multistability of ecological communities across environmental gradients"
    Ecological Monographs. (2021)
  • 10. Masuya H, Usuda D, Nakata H, Yuhara N, Kurihara K, Namiki Y, Iwase S, Takada T, Tanaka N, Suzuki K, Yamagata Y, Kobayashi N, Yoshiki A, Kushida T
    "Establishment and application of information resource of mutant mice in RIKEN BioResource Research Center"
    Laboratory Animal Research. 37(6), (2021)

Related Links

Lab Members

Principal investigator

Hiroshi Masuya
Division Director

Core members

Shigeru Iwase
Senior Research Scientist
Tatsuya Kushida
Research Scientist
Kenta Suzuki
Research Scientist
Yuki Yamagata
Research Scientist
Toyoyuki Takada
Research & Development Scientist
Sotaro Takano
Research & Development Scientist
Norio Kobayashi
Research & Development Scientist
Naomi Yuhara
Technical Staff II
Keiko Kurihara
Technical Staff II
Daiki Usuda
Technical Staff II
Yuri Namiki
Technical Staff II

Contact Information

Room 113, Information and JCM Building,
3-1-1 Koyadai,
Tsukuba, Ibaraki,
305-0074 Japan
Tel: +81-(0)29-829-9112
Fax: +81-(0)29-836-9337
Email: hiroshi.masuya@riken.jp

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