Research Summary

Selected Publications

• 1. Otaki N, Motomura Y, Terooatea T, Thomas Kelly S, Mochizuki M, Takeno N, Koyasu S, Tamamitsu M, Sugihara F, Kikuta J, Kitamura H, Shiraishi Y, Miyanohara J, Nagano Y, Saita Y, Ogura T, Asano K, Minoda A, Moro K.:
  "Activation of ILC2s through constitutive IFNγ signaling reduction leads to spontaneous pulmonary fibrosis"
  Nat Commun, 2023 14(1):8120
• 2. Hikichi Y, Motomura Y, Takeuchi O, Moro K.:
  "Posttranscriptional regulation of ILC2 homeostatic function via tristetraprolin."
  J Exp Med. 2021 Dec 6;218(12)
• 3. Momiuchi Y, Motomura Y, Suga E, Mizuno H, Kikuta J, Morimoto A, Mochizuki M, Otaki N, Ishii M, Moro K.:
  "Group 2 innate lymphoid cells in bone marrow regulate osteoclastogenesis in a reciprocal manner via RANKL, GM-CSF and IL-13."
  Int Immunol. 2021 Oct 29;33(11)
• 4. Miyajima Y, Ealey KN, Motomura Y, Mochizuki M, Takeno N, Yanagita M, Economides AN, Nakayama M, Koseki H, Moro K.:
  "Effects of BMP7 produced by group 2 innate lymphoid cells on adipogenesis."
  Int Immunol. 2020 May 30;32(6)
• 5. Sasaki T, Moro K, Kubota T, Kubota N, Kato T, Ohno H, Nakae S, Saito H, Koyasu S.:
  "Innate Lymphoid Cells in the Induction of Obesity."
  Cell Rep. 2019 Jul 2;28(1)
• 6. Kobayashi T, Voisin B, Kim DY, Kennedy EA, Jo JH, Shih HY, Truong A, Doebel T, Sakamoto K, Cui CY, Schlessinger D, Moro K, Nakae S, Horiuchi K, Zhu J, Leonard WJ, Kong HH, Nagao K.:
  "Homeostatic Control of Sebaceous Glands by Innate Lymphoid Cells Regulates Commensal Bacteria Equilibrium."
  Cell. 2019 Feb 21;176(5)
• 7. Koga S, Hozumi K, Hirano KI, Yazawa M, Terooatea T, Minoda A, Nagasawa T, Koyasu S, Moro K.:
  "Peripheral PDGFRα+gp38+ mesenchymal cells support the differentiation of fetal liver-derived ILC2."
  J Exp Med. 2018 Jun 4;215(6)
• 8. Moro K, Kabata H, Tanabe M, Koga S, Takeno N, Mochizuki M, Fukunaga K, Asano K, Betsuyaku T, Koyasu S.:
  "Interferon and IL-27 antagonize the function of group 2 innate lymphoid cells and type 2 innate immune responses."
  Nat Immunol. 2016 17(1):76-86

Recent Research Results

• 

  Mar. 5, 2024
  Unlocking the secrets of lung fibrosis with a new mouse model

• 

  Jul. 3, 2019
  Innate immune responses to high-fat diets lead to obesity

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  Nov. 24, 2015
  How the body stops an immune response from triggering allergic diseases

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