RIKEN Center for Advanced Intelligence Project Medical-risk Avoidance based on iPS Cells Team
Team Director: Naonori Ueda (D.Eng.)
Research Summary
In cooperation with the iPS cell research institute (CiRA) of Kyoto university, by using AI and iPS cell technologies jointly, this team will research and develop technologies for predicting Altzheimer's disease risk which is becoming social urgent matter. Moreover, we will conduct research develop technologies to ensure the safety of iPS cells themselves. The former results will improve the possibility of risk prediction of Altzhimer's disease with solution, and the latter will enable the stock of high quality iPS cells for regenerative medicine.
Research Subjects:
- Identification of Alzheimer's risk control drug
- Genome abnormality verification technology
- Abnormality prediction technology for iPS cells and cells derived from iPS cells
Main Research Fields
- Clinical Medicine
Related Research Fields
- Computer Science
- Geosciences
Selected Publications
Papers with an asterisk(*) are based on research conducted outside of RIKEN.
- 1.
Niwa, R., Matsumoto, T., Liu, Y.A., Kawato, M., Kondo, T., Tsukita, K., Inoue, H., Maurissen, L.T., and Woltjen, K.:
"Enrichment of allelic editing outcomes by Prime Editing in iPS cells"
bioRxiv, 2024. - 2.
Nonaka, H., Kondo, T., Suga, M., Yamanaka, R., Sagara, Y., Tsukita, K., Mitsutomi, N., Homma, K., Saito, R., Miyoshi, F., Ohzeki, H., Okuyama, M., and Inoue, H.:
"Induced pluripotent stem cell-based assays recapture multiple properties of human astrocytes"
Journal of Cellular and Molecular Medicine,28(7), e18214, 2024. - 3
Okunomiya, T., Watanabe, D., Banno, H., Kondo, T., Imamura, K., Takahashi, R., and Inoue, H.:
"Striosome circuitry stimulation inhibits striatal dopamine release and locomotion"
in press
Related Links
Lab Members
Principal investigator
- Naonori Ueda
- Team Director
Core members
- Ayako Nagahashi
- Technical Scientist
- Yoko Ishida
- Technical Staff I
- Tamami Nakanishi
- Technical Staff I
- Haruhisa Inoue
- Senior Visiting Scientist
- Takuya Yamamoto
- Visiting Scientist
Contact Information
Center for iPS Cell Research and Application, Kyoto University
Email: naonori.ueda@riken.jp