RIKEN Center for Biosystems Dynamics Research Laboratory for AI Biology
Team Director: Haruka Ozaki (Ph.D.)
Research Summary
Through AI biology, we aim to create an environment in life sciences research where AI and robotics are a commonplace part of everyday work. By developing, implementing, and validating these technologies in real life settings for life science research, we seek to demonstrate a range of new possibilities achievable only through non-human approaches like AI and robotics. Furthermore, we aspire to establish new theories and academic disciplines with these findings.
Main Research Fields
- Complex Systems
Related Research Fields
- Informatics
- Biological Sciences
- Biology
- Life, health and medical informatics-related
- System genome science-related
Keywords
- AI Biology
- Laboratory Automation
- Research Automation
- Informatics for cell
Selected Publications
Papers with an asterisk(*) are based on research conducted outside of RIKEN.
- 1.
*Matsuzawa R, Kawahara D, Kashima M, et al.
"tomoseqr: A Bioconductor package for spatial reconstruction and visualization of 3D gene expression patterns based on RNA tomography."
PLOS ONE 20(1), e0311296 (2025) doi: 10.1371/journal.pone.0311296 - 2.
*Nakata S, Iwasaki K, Funato H, et al.
"Neuronal subtype-specific transcriptomic changes in the cerebral neocortex associated with sleep pressure."
Neuroscience Research 207, 13-25 (2024) doi: 10.1016/j.neures.2024.03.004 - 3.
*Tahara S, Tsuchiya T, Matsumoto H, Ozaki H.
"Transcription factor-binding k-mer analysis clarifies the cell type dependency of binding specificities and cis-regulatory SNPs in humans."
BMC Genomics 24(1), 597 (2023) doi: 10.1186/s12864-023-09692-9 - 4.
Arai Y, Takahashi K, Horinouchi T, et al.
"SAGAS: Simulated annealing and greedy algorithm scheduler for laboratory automation."
SLAS Technology 28(4), 264-277 (2023) doi: 10.1016/j.slast.2023.03.001 - 5.
*Tsuchiya T, Hori H, Ozaki H.
"CCPLS reveals cell-type-specific spatial dependence of transcriptomes in single cells."
Bioinformatics 38(21), 4868-4877 (2022) doi: 10.1093/bioinformatics/btac599 - 6.
Itoh TD, Horinouchi T, Uchida H, et al.
"Optimal Scheduling for Laboratory Automation of Life Science Experiments with Time Constraints."
SLAS Technology 26(6), 650-659 (2021) doi: 10.1177/24726303211021790 - 7.
*Minoshima F, Ozaki H, Odaka H, Tateno H.
"Integrated analysis of glycan and RNA in single cells."
iScience 24(8), 102882 (2021) doi: 10.1016/j.isci.2021.102882 - 8.
Ozaki H, Hayashi T, Umeda M, Nikaido I.
"Millefy: visualizing cell-to-cell heterogeneity in read coverage of single-cell RNA sequencing datasets."
BMC Genomics 21(1), 177 (2020) doi: 10.1186/s12864-020-6542-z
Related Links
Lab Members
Principal investigator
- Haruka Ozaki
- Team Director
Core members
- Yoshinori Hayakawa
- Research Fellow
- Saeko Tahara
- Research Fellow
- Hirofumi Kariyayama
- Visiting Researcher
- Yu Chinen
- Research Part-time Worker I
- Yuya Tahara
- Student Trainee
- Ryosuke Matsuzawa
- Student Trainee
- Ryo Ishibashi
- Student Trainee
- Haruto Ijiri
- Student Trainee
- Kota Murakami
- Student Trainee
- Junnosuke Imai
- Student Trainee
- Koki Tachibana
- Student Trainee
- Genki Kanda
- Senior Visiting Scientist
- Miwa Elharar
- Assistant
Contact Information
Integrated Innovation Building
6-7-1 Minatojima-minamimachi, Chuo-ku, Kobe, Hyogo 650-0047, Japan
Email: ai-biology@ml.riken.jp