Research Summary

Selected Publications

• 1. Kawasumi-Kita A, Lee SW, Ohtsuka D, et al.
  "hoxc12/c13 as key regulators for rebooting the developmental program in Xenopus limb regeneration."
  Nature Communications 15(1), 3340 (2024) doi: 10.1038/s41467-024-47093-y
• 2. Morishita Y, Lee SW, Suzuki T, et al.
  "An archetype and scaling of developmental tissue dynamics across species."
  Nature Communications 14(1), 8199 (2023) doi: 10.1038/s41467-023-43902-y
• 3. Ohtsuka D, Kida N, Lee SW, et al.
  "Cell disorientation by loss of SHH-dependent mechanosensation causes cyclopia."
  Science Advances 8(28), eabn2330 (2022) doi: 10.1126/sciadv.abn2330
• 4. Kawahira N, Ohtsuka D, Kida N, et al.
  "Quantitative analysis of 3D tissue deformation reveals key cellular mechanism associated with initial heart looping."
  Cell Reports 30, 3889-3903 (2020) doi: 10.1016/j.celrep.2020.02.071
• 5. Lee SW, Morishita Y.:
  "Possible roles of mechanical cell elimination intrinsic to growing tissues from the perspective of tissue growth efficiency and homeostasis."
  Plos Computational Biology 13(7), e1005651 (2017) doi: 10.1371/journal.pcbi.1005651
• 6. Morishita Y, Hironaka K, Lee SW, et al.
  "Reconstructing 3D deformation dynamics for curved epithelial sheet morphogenesis from positional data of sparsely-labeled cells."
  Nature Communications 8, 15 (2017) doi: 10.1038/s41467-017-00023-7
• 7. Morishita Y, Kuroiwa A, Suzuki T.:
  "Quantitative analysis of tissue deformation dynamics reveals three characteristic growth modes and globally aligned anisotropic tissue deformation during chick limb development."
  Development 142(9), 1672-1683 (2015) doi: 10.1242/dev.109728
• 8. Morishita Y, Suzuki T.:
  "Bayesian inference of whole-organ deformation dynamics from limited space-time point data."
  Journal of Theoretical Biology 357, 74-85 (2014) doi: 10.1016/j.jtbi.2014.04.027
• 9. Hironaka K, Morishita Y.:
  "Encoding and decoding of positional information in morphogen-dependent patterning."
  Current Opinion in Genetics and Development 22(6), 553-561 (2012) doi: 10.1016/j.gde.2012.10.002
• 10. Morishita Y, Iwasa Y.:
  "Coding Design of Positional Information for Robust Morphogenesis."
  Biophysical Journal 101(10), 2324-2335 (2011) doi: 10.1016/j.bpj.2011.09.048

Recent Research Results

• 

  Mar. 28, 2024
  Comparing how limbs develop in chicks and frogs

• 

  Oct. 4, 2022
  Mechanical sensors help coordinate cell organization during eye development

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