Research Summary

Selected Publications

• 1. Morita S, Kondo T, Tokuda H, Kaneda Y, Izumo T, Nakao Y, Inoue H.
  "Polyunsaturated fatty acids in lipid membranes regulate human neuronal function and amyloid-β production"
  iScience (2025)
• 2. Otsuka Y, Imamura K, Oishi A, Asakawa K, Kondo T, Nakai R, Suga M, Inoue I, Sagara Y, Tsukita K, Teranaka K, Nishimura Y, Watanabe A, Umeyama K, Okushima N, Mitani K, Nagashima H, Kawakami K, Muguruma K, Tsujikawa A and Inoue H.
  "Phototoxicity avoidance is a potential therapeutic approach for retinal dystrophy caused by EYS dysfunction"
  JCI Insight (2024)
• 3. Nonaka H, Kondo T, Suga M, Yamanaka R, Sagara Y, Tsukita K, Mitsutomi N, Homma K, Saito R, Miyoshi F, Ohzeki H, Okuyama M, Inoue H.
  " Induced pluripotent stem cell-based assays recapture multiple properties of human astrocytes"
  Journal of Cellular and Molecular Medicine (2024)
• 4. Suzuki H, Egawa N, Imamura K, Kondo T, Enami T, Tsukita K, Suga M, Yada Y, Shibukawa R, Takahashi R, Inoue H.
  "Mutant α-synuclein causes death of human cortical neurons via ERK1/2 and JNK activation."
  Molecular Brain (2024)
• 5. Suong D, Imamura K, Kato Y, Inoue H.
  "Design of neural organoids engineered by mechanical forces."
  IBRO Neuroscience Reports (2024)
• 6. Kondo T, Inoue I, Umeyama K, Watanabe M, Matsunari H, Uchikura A, Nakano K, Tsukita K, Imamura K, Nagashima H, Inoue H.
  "A Transgenic Pig Model With Human Mutant SOD1 Exhibits the Early Pathology of Amyotrophic Lateral Sclerosis."
  Laboratory Investigation (2023)
• 7. Kondo T, Yada Y, Ikeuchi T, Inoue H:
  "CDiP technology for reverse engineering of sporadic Alzheimer’s disease"
  l of Human Genetic(2022)
• 8. Otsuka Y, Imamura K, Oishi A, Kondo T, Suga M, Yada Y, Shibukawa R, Okanishi Y, Sagara Y, Tsukita K, Tsujikawa A, Inoue H:
  "One-step induction of photoreceptor-like cells from human iPSCs by delivering transcription factors"
  iScience (2022)
• 9. Kondo T, Hara N, Koyama S, Yada Y, Tsukita K, Nagahashi A, Ikeuchi T, Ishii K, Asada T, Arai T, Yamada R, Japanese Alzheimer's Disease Neuroimaging Initiative (J-ADNI), Alzheimer’s Disease Neuroimaging Initiative (ADNI), Inoue H:
  "Dissection of the polygenic architecture of neuronal Aβ production using a large sample of individual iPSC lines derived from Alzheimer’s disease patients"
  Nature Aging (2022)
• 10. Yada Y, Suga M, Shibukawa R, Sagara Y, Okanishi Y, Enami T, Tsukita K, Kondo T, Imamura K, Sugihara G, Murai T, Inoue H
  "Establishment of induced pluripotent stem cells from schizophrenia discordant fraternal twins"
  Stem Cell Research (2021)

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