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RIKEN Center for Brain Science Support Unit for Functional Magnetic Resonance Imaging

Unit Leader: Tomohisa Okada (M.D., Ph.D.)

Research Summary

Tomohisa Okada

We provide technical assistance and engages in research and development for non-invasive experiments for humans and animals using 7 Tesla and 3 Tesla magnetic resonance imaging (MRI) systems. We also offer a “Commissioned Test” service to external parties. The MRI measurements include functional MRI, structural imaging including DTI and QSM, and MRS for measuring neurochemicals like glutamate and GABA. Additionally, various stimulus presentation devices (projectors, earphones, electrical stimulators, etc.) are available, and we can record participants’ responses and physiological states, such as button-press responses, heart rate, respiration, pupil diameter, eye movement, etc.

Main Research Fields

  • Biological Sciences

Related Research Fields

  • Humanities & Social Sciences
  • Medicine, Dentistry & Pharmacy
  • Cognitive science-related
  • Function of nervous system-related
  • Basic brain sciences-related

Keywords

  • Magnetic resonance imaging system
  • Brain functional and structural imaging
  • Neurochemical measurement
  • Neuropsychology
  • Cognitive and brain science

Selected Publications

Papers with an asterisk(*) are based on research conducted outside of RIKEN.

  • 1.Ma N, Harasawa N, Ueno K, Cheng K, and Nakahara H.
    "Decision-Making with Predictions of Others' Likely and Unlikely Choices in the Human Brain."
    J Neurosci. 2024 Sep 11;44(37):e2236232024.
  • 2.*Okada T, Kuribayashi H, Urushibata Y, Fujimoto K, Akasaka T, Seethamraju RT, Ahn S, and Isa T.
    "GABA, glutamate and excitatory-inhibitory ratios measured using short-TE STEAM MRS at 7-Tesla: Effects of macromolecule basis sets and baseline parameters."
    Heliyon. 2023 Jul 15;9(7):e18357.
  • 3.*Okada T, Fujimoto K, Fushimi Y, Akasaka T, Thuy DHD, Shima A, Sawamoto N, Oishi N, Zhang Z, Funaki T, Nakamoto Y, Murai T, Miyamoto S, Takahashi R, and Isa T.
    "Neuroimaging at 7 Tesla: a pictorial narrative review."
    Quant Imaging Med Surg. 2022 Jun;12(6):3406-3435.
  • 4.*Okada T, Handa S, Ding B, Urayama SI, Fujimoto K, Shima A, Yoshii D, Ayaki T, Sawamoto N, Takahashi R, Onoe H, Isa T, and Petropoulos L.
    "Insertable inductively coupled volumetric coils for MR microscopy in a human 7T MR system."
    Magn Reson Med. 2022 Mar;87(3):1613-1620.
  • 5.Sakai H, Ueda S, Ueno K, and Kumada T.
    "Neuroplastic Reorganization Induced by Sensory Augmentation for Self-Localization During Locomotion."
    Front Neuroergon. 2021 Aug 13;2:691993.
  • 6.Ueda S, Sakai H, Ueno K, Cheng K, and Kumada T.
    "Cerebellar activation associated with model-based estimation of tool-use consequences."
    Behav Brain Funct. 2019 Apr 16;15(1):8.
  • 7.Nakatani H, Ogawa A, Suzuki C, Asamizuya T, Ueno K, Cheng K, and Okanoya K.
    "Perceived moral traits of others differentiate the neural activation that underlies inequity-aversion."
    Sci Rep. 2017 Feb 23;7:43317.
  • 8.Katahira K, Matsuda YT, Fujimura T, Ueno K, Asamizuya T, Suzuki C, Cheng K, Okanoya K, and Okada M.
    "Neural basis of decision making guided by emotional outcomes."
    J Neurophysiol. 2015 May 1;113(9):3056-68.
  • 9.Sun P, Gardner JL, Costagli M, Ueno K, Waggoner RA, Tanaka K, and Cheng K.
    "Demonstration of tuning to stimulus orientation in the human visual cortex: a high-resolution fMRI study with a novel continuous and periodic stimulation paradigm."
    Cereb Cortex. 2013 Jul;23(7):1618-29.
  • 10.Sun P, Ueno K, Waggoner RA, Gardner JL, Tanaka K, and Cheng K.
    "A temporal frequency-dependent functional architecture in human V1 revealed by high-resolution fMRI."
    Nat Neurosci. 2007 Nov;10(11):1404-6.

Recent Research Results

Related Links

Lab Members

Principal investigator

Tomohisa Okada
Unit Leader

Core members

R. Allen Waggoner
Senior Technical Scientist
Ken-ichi Ueno
Technical Scientist
Chisato Suzuki
Technical Scientist

Contact Information

Riken CBS (W-D54)
207 East research building, Center for Brain Science
2-1 Hirosawa, Wako, Saitama 351-0198, Japan
Email: fmri@riken.jp

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