Research Summary

Main Research Fields

• Complex Systems

Related Research Fields

• Chemistry
• Agricultural Sciences
• Informatics
• Environmental Science
• Interdisciplinary Science & Engineering
• Mathematical & Physical Sciences
• Biological Sciences
• Life Sciences
• Environmental Analysis & Modeling
• Aquatic Ecosystem

Keywords

• Environmental analysis
• Data science
• Magnetic resonance
• Symbiosis
• Homeostasis

Selected Publications

• 1. Ito, K., Xu, X. and Kikuchi, J.^*
  "Improved Prediction of Carbonless NMR Spectra by the Machine Learning of Theoretical and Fragment Descriptors for Environmental Mixture Analysis"
  Anal. Chem. 93, 6901-6906 (2021).
• 2. Kikuchi, J.^* and Yamada, S.
  "The exposome paradigm to predict environmental health in terms of systemic homeostasis and resource balance based on NMR data science"
  RSC Adv. 11, 30426-30447 (2021).
• 3. Ichihashi, Y.^*, Date, Y., Shino, A., Shimizu, T., Shibata, A., Kumaishi, K., Funahashi, F., Wakayama, K., Yamazaki, K., Um,ezawa, A., Sato, T., Kobayashi, M., Kamimura, M., Kusano, M., Che, F.-S., O’Brien, M., Tanoi, K., Hayashi, M., Nakamura, R., Shirasu, K., Kikuchi, J. and Nihei, N.
  "Multi-omics analysis on an agroecosystem reveals the significant role of organic nitrogen to increase agricultural crop yield"
  Proc. Natl. Acad. Sci. USA117, 14552-14560 (2020).
• 4.Mega, R., Abe, F., Kim, J.-S., Tsuboi, Y., Tanaka, K., Kobayashi, H., Sakata, Y., Hanada, K., Tsujimoto, H., Kikuchi, J., Cutler, S. R. and Okamoto, M.^*
  "Tuning water use efficiency and drought tolerance in wheat using ABA receptors"
  Nature Plants 5, 153-159 (2019).
• 5.Ito, K., Obuchi, Y., Chikayama, E., Date, Y. and Kikuchi, J.^*
  "Exploratory machine-learned theoretical chemical shifts can closely predict metabolic mixture signals"
  Chem. Sci. 9, 8213-8220 (2018).
• 6. Date, Y.* and Kikuchi, J.^*
  "Application of a deep neural network to metabolomics studies and its performance in determining important variables"
  Anal. Chem. 90, 1805-1810 (2018).
• 7. Oita, A., Oshima, T., Tsuboi, Y., Moriya, S., Date, Y. and Kikuchi, J.^*
  "Profiling physicochemical and planktonic features from discretely/continuously sampled surface water"
  Sci. Total Environ. 636, 12-19 (2018).
• 8. Komatsu, T., Ohishi, R., Shino, A. and Kikuchi, J.^*
  "Structure and metabolic flow analysis of molecular complexity in 13C-labeled tree by 2D and 3D-NMR"
  Angew. Chem. Int. Ed. 55, 6000-6003 (2016).
• 9. Furusawa, Y., Obata, Y., Fukuda, S.^*, Endo, T., Nakato, G., Takahashi, D., Nakanishi, Y., Uetake, C., Kato, K., Kato, T., Takahashi, M., Fukuda, N., Murakami, S., Miyauchi, E., Hino, S., Atarashi, K., Onawa, S., Fujimura, Y., Lockett, T., Clarke, J. M., Topping, D. L., Tomita, M., Hori, S., Ohara, O., Morita, T., Koseki, H., Kikuchi, J., Honda, K., Hase, K.^* and Ohno, H.
  "Commensal microbe-derived butyrate induces colonic regulatory T cells"
  Nature 504, 446-450 (2013).
• 10. Fukuda, S., Toh, H., Hase, K., Nakanishi, Y., Oshima, K., Yoshimura, K., Tobe, T., Clarke, J. M., Topping, D. L., Suzuki, T., Taylor, T. D., Itoh, K., Kikuchi, J., Morita, H., Hattori, M.^* and Ohno, H.^*
  "Bifidobacteria protect from enteropathogenic infection through production of acetate"
  Nature 469, 543-547 (2011).

Recent Research Results

• 

  Jun. 17, 2016
  Torrefied biomass improves poor soil

• 

  Mar. 28, 2014
  Seasonal seaweed highlights chemical diversity

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