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RIKEN SPring-8 Center Forensic Science Group

Group Director: Yasuo Seto (Ph.D.)

Research Summary

Yasuo  Seto(Ph.D.)

Forensic science uses technology to establish facts in criminal investigations based on witness testimony. The scientific investigation consists of both a review of conditions on-site at crime scenes and an examination of relevant evidence in a laboratory.

Synchrotron radiation (SR) offers advanced analysis technology that can shed light on problems that cannot be resolved using conventional forensic science techniques. We verify the results of the SR analysis used in forensic science, discuss the capabilities of SR with external organizations in the forensic science field, and build frameworks for joint research focused on driving improvements in analytical capabilities and investigation results.

Furthermore, we are building the most advanced SR analysis system and developing leading-edge forensic science technology. The new capabilities will timely respond to the tough requests from criminal investigations and prosecutions.

Main Research Fields

  • Interdisciplinary Science & Engineering

Related Research Fields

  • Complex Systems
  • Chemistry
  • Engineering
  • Biology
  • Medicine, Dentistry & Pharmacy
  • Quantum beam science
  • Social/Safety system science
  • Applied chemistry


  • Synchrotron radiation
  • Forensic Science
  • Scientific investigation
  • X-ray/electron spectroscopy
  • Safety engineering

Selected Publications

Papers with an asterisk(*) are based on research conducted outside of RIKEN.

  • 1.*Saito, M., Uchida, N., Furutani, S., Murahashi, M., Espulgar, W., Nagatani, N., Nagai, H., Kondo, S., Uzawa,H., Seto, Y., Tamiya, E.:
    "Field-deployable rapid multiple biosensing system for detection of chemical and biological warfare agent"
    Microsystems & Nanoengineering, 4 (2018) DOI:10.1038/micronano.2017.82
  • 2.*Seto, Y.
    "On-site detection of chemical warfare agents"
    'Handbook of the Toxicology of Chemical Warfare Agents', 2nd ed., ed. by R. C. Gupta, Elsevier, Amsterdam, 2015, Chapter 60, pp.897-914
  • 3.*Seto, Y.
    "R&D of on-site decontamination system for biological and chemical warfare agents (Review)"
    Journal of Health Sciences, 57, 311-333 (2011)
  • 4.*Seto, Y., Sekiguchi, H.,. Maruko, H., Yamashiro, S., Sano, Y., Takayama, Y., Sekioka, R., Yamaguchi, S., Kishi, S., Sato, T., Sekiguchi, H., Iura, K., Nagashima, H., Nagoya, T., Tsuge, T., Okumura, A., et. al.:
    "Sensitive and comprehensive detection of chemical warfare agents in air by atmospheric pressure chemical ionization ion trap tandem mass spectrometry with counter-flow introduction"
    Analytical Chemistry, 86, 4316-4326 (2014)
  • 5.*Komano, A., Hirakawa, T., Sato, K., Kishi, S., Nishimoto, C. K., Mera, N., Kugishima, M., Sano, T., Negishi, N., Ichinose, H., Seto, Y., Takeuchi, T.:
    "Titanium dioxide photocatalytic decomposition of VX in aquous phase"
    Applied Catalysis B: Environmental, 134-135, 19-25 (2013)
  • 6.*Inami, H., Tsuge, K., Matsuzawa, M., Sasaki, Y., Togashi, S., Komano, A., Seto, Y.:
    "Semi-automated bacterial spore detection system with micro-fluidic chips for aerosol collection, spore treatment, and ICAN DNA detection"
    Biosensors and Bioelectronics, 24, 3299-3305 (2009)
  • 7.*Seto, Y.
    "False cyanide detection"
    Analytical Chemistry, 74, 134-141A (2002)
  • 8.*Seto, Y.
    "Determination of volatile substances in biological samples by head-space gas chromatography (Review)"
    Journal of Chromatography A, 674, 25-62 (1994)
  • 9.*Seto, Y., Guengerich, F. P.:
    "Partitioning between N-dealkylation and N-oxygenation in the oxidation of N,N-dialkylanilines catalyzed by cytochrome P450 2B1"
    Journal of Biological Chemistry, 268, 9986-9997 (1993)
  • 10.*Seto., Y., Shinohara, T.:
    "Structure-activity relationship of reversible cholinesterase inhibitors including paraquat"
    Archives of Toxicology, 62, 37-40 (1988)

Lab Members

Principal investigator

Yasuo Seto
Group Director

Core members

Takahiro Iwai
Research Scientist
Shimpei Watanabe
Research Scientist


Position Deadline
Seeking a few Research Scientist or Postdoctoral Researcher position (C21-0205) Open until filled

Contact Information

SPring-8 Center, Physical science research building
1-1-1 Kouto, Sayo-cho
Sayo-gun, Hyogo
679-5148 Japan
Tel: +81-(0)791-58-0802(ex. 7906)
Fax: +81-(0)791-58-2898
Email: seto.y [at] spring8.or.jp