RIKEN Baton Zone Program Bio-chemical Production Laboratory
Team Leader Yoshihide Yachi
Deputy Team Leader Tomokazu Shirai (Ph.D.)
Research Summary
We are studying the following in order to produce bio-butadiene by microorganisms and realize bio-polybutadiene.
- 1.Improve the activity of butadiene-producing microorganisms.
The enzyme of the key reaction is highly activated by the enzyme engineering method, and at the same time, the intracellular metabolism is optimized by using the synthetic biology technology to improve the productivity. - 2.Purification of biobutadiene produced in the gas phase of the fermenter
By-products of fermentation may include polymerization inhibitors. Based on the polymerization technology, we will develop a concentration/purification process and develop a process that can produce commercially viable butadiene.
[Integrated Collaborative Research with Zeon Corporation]
Main Research Fields
- Engineering
Related Research Fields
- Chemistry
- Biology
- Biofunction/Bioprocess
Keywords
- enzyme engineering
- synthetic biology
- fermentation
- microorganism
- butadiene
Lab Members
Principal investigator
- Yoshihide Yachi
- Team Leader
Core members
- Tomokazu Shirai
- Deputy Team Leader
- Niina Kurokawa
- Visiting Scientist
- Kunihiro Goto
- Visiting Scientist
- Takumi Sonoda
- Visiting Scientist
- Yukio Takagishi
- Visiting Scientist
- Leo Tsunoi
- Visiting Scientist
- Koya Nukaga
- Visiting Scientist
- Miyuki Hayashi
- Visiting Technician
- Mariko Fujikawa
- Visiting Technician
- Mami Yoshida
- Visiting Technician
- Miki Ugawa
- Administrative Part-time Worker I
Contact Information
1-6 Suehiro-cho, Tsurumi-ku,
Yokohama, Kanagawa,
240-0035, Japan
Tel:+81-(0)45-633-8007
Email: yoshihide.yachi [at] riken.jp