RIKEN Information R&D and Strategy Headquarters Life Science Data Sharing Unit
Unit Leader: Shuichi Onami (D.V.M., Ph.D.)
Research Summary

To promote open science in the life sciences, the Unit conducts research and development to collect a wide variety of research data in the life sciences produced by RIKEN and facilitate secondary use. With all of RIKEN’s life science research centers’ participation, we will develop the foundation for open science in the life sciences and pioneer a new style of life sciences.
Main Research Fields
- Informatics
Related Research Fields
- Life / Health / Medical informatics
- System genome science
- Multimedia database
- Biological Sciences
- Biology
- Medicine, Dentistry & Pharmacy
- Agricultural Sciences
Keywords
- Open science
- Data integration
- Life science data
- Biological data science
- Metadata
Selected Publications
- 1.
Fukushima, A., Takahashi, M., Nagasaki, H., Aono, Y., Kobayashi, M., Kusano, M., Saito, K., Kobayashi, N., and Arita, M.:
"Development of RIKEN Plant Metabolonome MetaDatabase"
Plant and Cell Physiology 63(3), 433-440. (2021). doi: 10.1093/pcp/pcab173 - 2.
Swedlow, J. R., Kankaanpää, P., Sarkans, U., Goscinski, W., Galloway, G., Malacrida, L., Sullivan, R. P., Härtel, S., Brown, C. M., Wood, C., Keppler, A., Paina, F., Loos, B., Zullino, S., Longo, D. L., Aime, S., and Onami, S.:
"A Global view of standards for open image data formats and repositories"
Nature Methods 18, 1440-1446. (2021). doi: 10.1038/s41592-021-01113-7 - 3.
Kita, Y., Nishibe, H., Wang, Y., Hashikawa, T., Kikuchi, S. S., U, M., Yoshida, A. C., Yoshida, C., Kawase, T., Ishii, S., Skibbe, H., and Shimogori, T.:
"Cellular-resolution gene expression profiling in the neonatal marmoset brain reveals dynamic species- and region-specific differences"
Proceedings of the National Academy of Sciences 118(18), e2020125118. (2021). doi: 10.1073/pnas.2020125118 - 4.
Abugessaisa, I., Ramilowski, JA., Lizio, M., Severin, J., Hasegawa, A., Harshbarger, J., Kondo, A., Noguchi, S., Yip, C., Ooi, J., Tagami, M., Hori, F., Agrawal, S., Hon, C., Cardon, M., Ikeda, S., Ono, H., Bono, H., Kato, M., Hashimoto. K., Bonetti. A., Kato, M., Kobayashi, N., Shin, J., de Hoon, M., Hayashizaki, Y., Carninci, P., Kawaji, H., and Kasukawa, T.:
"FANTOM enters 20th year: expansion of transcriptomic atlases and functional annotation of non-coding RNAs"
Nucleic Acids Research 49, gkaa1054. (2020). doi: 10.1093/nar/gkaa1054 - 5.
Tsugawa, H., Ikeda, K., Takahashi, M., Satoh, A., Mori, Y., Uchino, H., Okahashi, N., Yamada, Y., Tada, I., Bonini, P., Higashi, Y., Okazaki, Y., Zhou, Z., Zhu, Z., Koelmel, J., Cajka, T., Fiehn, O., Saito, K., Arita, M., and Arita, M.:
"A lipidome atlas in MS-DIAL 4"
Nature Biotechnology 38, 1159–1163 (2020). doi: 10.1038/s41587-020-0531-2 - 6.
Tanaka, N., and Masuya, H.:
"An atlas of evidence-based phenotypic associations across the mouse phenome"
Scientific Reports 10, 3957 (2020). doi: 10.1038/s41598-020-60891-w - 7.
Morita, M., Shimokawa, K., Nishimura, M., Nakamura, S., Tsujimura, Y., Takemoto, S., Tawara, T., Yokota, H., Wemler, S., Miyamoto, D., Ikeno, H., Sato, A., Furuichi, T., Kobayashi, N., Okumura, Y., Yamaguchi, Y., and Okamura- Oho, Y.:
"ViBrism DB: an interactive search and viewer platform for 2D/3D anatomical images of gene expression and co-expression networks"
Nucleic Acids Research 47(D1), D859-D866 (2019). doi: 10.1093/nar/gky951 - 8.
Kobayashi, N., Kume, S., Lenz, K., and Masuya, H.:
"RIKEN MetaDatabase: a database platform for health care and life sciences as a microcosm of linked open data cloud"
International Journal on Semantic Web and Information Systems 14(1), 140-164 (2018). doi: 10.4018/IJSWIS.2018010106 - 9.
Shimogori, T., Abe, A., Go, Y., Hashikawa, T., Kishi, N., Kikuchi, S. S., Kita, Y., Niimi, K., Nishibe, H., Okuno, M., Saga, K., Sakurai, M., Sato, M., Serizawa, T., Suzuki, S., Takahashi, E., Tanaka, M., Tatsumoto, S., Toki, M., U, M., Wang, Y., Windak, K. J., Yamagishi, H., Yamashita, K., Yoda, T., Yoshida, A. C., Yoshida, C., Yoshimoto, T., and Okano, H.:
"Digital gene atlas of neonate common marmoset brain"
Neuroscience Research 128, 1-13 (2018). doi: 10.1016/j.neures.2017.10.009 - 10.
Tohsato, Y., Ho, K. H. L., Kyoda, K., and Onami, S.:
"SSBD: a database of quantitative data of spatiotemporal dynamics of biological phenomena"
Bioinformatics 32(22), 3471-3479 (2016). doi: 10.1093/bioinformatics/btw417
Related Links
Lab Members
Principal investigator
- Shuichi Onami
- Unit Leader
Core members
- Masanori Arita
- Senior Research Scientist
- Takeya Kasukawa
- Senior Research Scientist
- Norio Kobayashi
- Senior Research Scientist
- Tomomi Shimogori
- Senior Research Scientist
- Hiroshi Masuya
- Senior Research Scientist
- Hideo Yokota
- Senior Research Scientist
- Yuki Yamagata
- Research Scientist
- Musashi Imaizumi
- Technical Staff I
Contact Information
2-2-3 Minatojima-minamimachi, Chuo-ku,
Kobe, Hyogo
650-0047 Japan
Email: sonami [at] riken.jp