RIKEN Center for Sustainable Resource Science Cell Function Research Team

Team Leader: Keiko Sugimoto (Ph.D.)

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Research Summary

We investigate how plants integrate developmental and environmental cues to maximise organ growth under the changing environment. We also explore how plants establish and maintain cellular differentiation status and how various stress stimuli override the developmental commitments to undergo cellular reprogramming. These strategies should allow us identify key modulators of organ growth and reprogramming, thus providing molecular basis for crop improvement.

Main Research Fields

Biology

Related Research Fields

Agricultural Sciences

Keywords

Cell proliferation
Cell differentiation
Cell dedifferentiation
totipotency
regeneration

Selected Publications

1. Chen Y, Ince YC, Kawamura A, Favero DS, Suzuki T, Sugimoto K.:
"ELONGATED HYPOCOTYL5-mediated light signalling promotes shoot regeneration in Arabidopsis thaliana."
Plant Physiol: kiae474. (2024)
2. Sakamoto Y, Kawamura A, Suzuki T, Segamai M, Polyn S, De Veylder K, Sugimoto K.:
"Transcriptional activation of auxin biosynthesis drives developmental reprogramming of differentiated cells."
Plant Cell: koac218. (2022)
3. Shibata M, Favero DS, Takebayashi R, Takebayashi A, Kawamura A, Rymen B, Hosokawa Y, Sugimoto K.:
"Trihelix transcription factors GTL1 and DF1 prevent aberrant root hair formation in an excess nutrient condition."
New Phytol 234(4): 1426-1441. (2022)
4. Lambolez A, Kawamura A, Takahashi T, Rymen B, Iwase A, Favero DS, Ikeuchi M, Suzuki T, Cortijo S, Jaeger KE, Wigge PA, Sugimoto K.:
"Warm temperature promotes shoot regeneration in Arabidopsis thaliana."
Plant Cell Physiol 63(5): 618-634. (2022)
5. Iwase A, Kondo Y, Laohavisit A, Takebayashi A, Ikeuchi M, Matsuoka K, Asahina M, Mitsuda N, Shirasu K, Fukuda H, Sugimoto K.:
"WIND transcription factors orchestrate wound-induced callus formation, vascular reconnection and defense response in Arabidopsis."
New Phytol 232:734-752. (2021)
6. Coleman D, Kawamura A, Ikeuchi M, Favero DS, Lambolez A, Rymen B, Iwase A, Suziki T, Sugimoto K.:
"The SUMO E3 ligase SIZ1 negatively regulates shoot regeneration in Arabidopsis."
Plant Physiol 184(1): 330-344. (2020)
7. Favero DS, Kawamura A, Shibata M, Takebayashi A, Jung JH, Suzuki T, Jaeger KE, Ishida T, Iwase A, Wigge PA, Neff MM, Sugimoto K.:
"AT-hook transcription factors restrict petiole growth by antagonizing PIFs."
Curr Biol 30(8):1454-1466.e6. (2020)
8. Rymen B, Kawamura A, Lambolez A, Inagaki S, Takebayashi A, Iwase A, Sakamoto Y, Sako K, Favero DS, Ikeuchi M, Suzuki T, Seki M, Kakutani T, Roudier F, Sugimoto K.:
"Histone acetylation orchestrates wound-induced transcriptional activation and cellular reprogramming in Arabidopsis."
Commun Biol 2:404 (2019)
9. Shibata M, Breuer B, Kawamura A, Clark N, Rymen B, Braidwood L, Morohashi K, Busch W, Benfey P, Sozzani R, Sugimoto K.:
"GTL1 and DF1 regulate root hair growth through transcriptional repression of ROOT HAIR DEFECTIVE 6-LIKE4 in Arabidopsis."
Development 145: dev159707. (2018)
10. Iwase A, Harashima H, Ikeuchi M, Rymen B, Ohnuma M, Komaki S, Morohashi K, Kurata T, Nakata M, Ohme-Takagi M, Grotewold E, Sugimoto K.:
"WIND1 promotes shoot regeneration through transcriptional activation of ESR1 in Arabidopsis."
Plant Cell 29(1): 54-69. (2017)