Research Summary

Selected Publications

• 1. Inaba, H., Shisaka, Y., Ariyasu, S., Sakakibara, E., Ueda, G., Aiba, Y., Shimizu, N., Sugimoto, H., and Shoji, O.:
  "Heme-substituted protein assembly bridged by synthetic porphyrin: achieving controlled configuration while maintaining rotational freedom”
  RSC Advances 14, 8829-8836 (2024).
• 2. Ando, R., Shimozono, S., Ago, H., Takagi, M., Sugiyama, M., Kurokawa, H., Hirano, M., Niino, Y., Ueno, G., Ishidate, F., Fujiwara, T., Okada, Y., Yamamoto, M., and Miyawaki, A.:
  "StayGold variants for molecular fusion and membrane-targeting applications”
  Nature Methods 21, 648-656 (2024).
• 3. Tsutsumi, E., Niwa, S., Takeda, R., Sakamoto, N., Okatsu, K., Fukai, S., Ago, H., Nagao, S., Sekiguchi, H., and Takeda, K.:
  "Structure of a putative immature form of a Rieske-type iron-sulfur protein in complex with zinc chloride”
  Communications Chemistry 6, 190 (2023)
• 4. Kutsukawa, R., Imaizumi, R., Suenaga-Hiromori, M., Takeshita, K., Sakai, N., Misawa, S., Yamamoto, M., Yamaguchi, H., Miyagi-Inoue, Y., Waki, T., Kataoka, K., Nakayama, T., Yamashita, S., and Takahashi, S.
  "Structure-based engineering of a short-chain cis-prenyltransferase to biosynthesize nonnatural all-cis-polyisoprenoids: molecular mechanisms for primer substrate recognition and ultimate product chain-length determination”
  The FEBS Journal 289(15), 4602-4621 (2022).
• 5. Maeki, M., Ito, S., Takeda, R., Ueno, G., Ishida, A., Tani, H., Yamamoto, M., and Tokeshi, M.:
  "Room-temperature crystallography using a microfluidic protein crystal array device and its application to protein-ligand complex structure analysis"
  Chemical Science 11, 9072-9087 (2020).
• 6. Nakasako, M., Kobayashi, A., Takayama, Y., Asakura, K., Oide, M., Okajima, K., Oroguchi, T., and Yamamoto, M.:
  "Methods and application of coherent X-ray diffraction imaging of noncrystalline particles"
  Biophysical reviews 12(2), 541-567 (2020).
• 7. Suga, M., Akita, F., Yamashita, K., Nakajima, Y., Ueno, G., Li, H., Yamane, T. Hirata, K., Umena, Y., Yonekura, S., Yu, L.-J., Murakami,H., Nomura, T., Kimura, T., Kubo, M., Baba, S., Kumasaka, T., Tono, K., Yabashi, M., Isobe, H., Yamaguchi, K., Yamamoto, M., Ago, H.,and Shen, J.-R.:
  "An oxyl/oxo mechanism for oxygen-oxygen coupling in PSII revealed by an x-ray free-electron laser"
  Science, 366, 334-338 (2019).
• 8. Hirata, K., Yamashita, K., Ueno. G., Kawano Y., Hasegawa, K., Kumasaka, T., and Yamamoto, M.:
  "ZOO: an automatic data-collection system for high-throughput structure analysis in protein microcrystallography"
  Acta Crystallographica Section D 75, 138-150 (2019).
• 9. Yamashita, K., Hirata, K., and Yamamoto, M.:
  "KAMO: towards automated data processing for microcrystals"
  Acta Crystallographica Section D 74, 441-449 (2018).
• 10. Hasegawa, K., Yamashita, K., Murai, T. Nuemket,N., Hirata, K., Ueno, G., Ago, H., Nakatsu, T., Kumasaka, T., and Yamamoto. M.:
  "Development of a dose-limiting data collection strategy for serial synchrotron rotation crystallography"
  Journal of Synchrotron Radiation 24 (1), 29-41 (2017).

Recent Research Results

• 

  Feb. 9, 2018
  A light touch for enzyme analysis

• 

  Dec. 15, 2017
  How bacteria avoid poisoning themselves

• 

  Sep. 22, 2017
  Watching enzymes inhale

• 

  Feb. 6, 2015
  Shining a gentle light on photosynthesis

• 

  Jul. 18, 2014
  X-ray studies without the damage

Lab Members

Contact Information