Research Summary

Selected Publications

• 1. Suga, M., Akita, F., Yamashita, K., Nakajima, Y., Ueno, G., Li, H., Yamane, T. Hirata, K., Umena, Y., Yonekura, S., Yu, L.-J., Murakami, H., Nomura, T., Kimura, T., Kubo, M., Baba, S., Kumasaka, T., Tono, K., Yabashi, M., Isobe, H., Yamaguchi, K., Yamamoto, M., Ago, H. and Shen, J.-R.:
  "An oxyl/oxo mechanism for oxygen-oxygen coupling in PSII revealed by an x-ray free-electron laser"
  Science, 366, 334-338 (2019)
• 2. Liu, X., Xu, X., Hilger, D., Aschauer, P., Tiemann, JKS., Du, Y., Liu, H., Hirata, K., Sun, X., Guixa-Gonzalez, R., Mathiesen, JM., Hildebrand, PW. & Kobilka, BK.:
  "Structural Insights into the Process of GPCR-G Protein Complex Formation"
  Cell 177, 1243-1251 (2019)
• 3. Basu, S., Olieric, V., Leonarski, F., Matsugaki, N., Kawano, Y., Takashi, T., Huang, C.-Y., Yamada, Y., Vera, L., Olieric, N., Basquin, J., Wojdyla, J. A., Bunk, O., Diederichs, K., Yamamoto, M. & Wang, M.:
  "Long-wavelength native-SAD phasing: opportunities and challenges"
  IUCrJ 6, 373-386 (2019)
• 4. Hirata, K., Yamashita, K., Ueno. G., Kawano Y., Hasegawa, K., Kumasaka, T., Yamamoto, M.:
  "ZOO: an automatic data-collection system for high-throughput structure analysis in protein microcrystallography"
  Acta Crystallographica Section D 75, 138-150 (2019)
• 5. Yamashita, K., Hirata, K., Yamamoto, M.:
  "KAMO: towards automated data processing for microcrystals."
  Acta Crystallographica Section D 74, 441-449 (2018)
• 6. Hasegawa, K., Yamashita, K., Murai, T. Nuemket,N., Hirata, K., Ueno, G., Ago, H., Nakatsu, T., Kumasaka, T., and Yamamoto. M.:
  "Development of a dose-limiting data collection strategy for serial synchrotron rotation crystallography"
  Journal of Synchrotron Radiation 24 (1), 29-41 (2017)
• 7. Kobayashi, A., Sekiguchi, Y., Takayama, Y., Oroguchi, T., Shirahama, K., Torizuka, Y., Manoda, M., Nakasako, M. and Yamamoto, M.:
  "TAKASAGO-6 apparatus for cryogenic coherent X-ray diffraction imaging of biological non-crystalline particles using X-ray free electron laser at SACLA."
  Review of Scientific Instruments 87, 053109 (2016)
• 8. Keitaro Yamashita, K., Pan, D., Okuda, T., Sugahara, M., Kodan, A., Yamaguchi, T., Murai, T., Gomi, K., Kajiyama, N., Mizohata, E., Suzuki, M., Nango, E., Tono, K., Joti, Y., Kameshima, T., Park, J., Song, C., Hatsui, T., Yabashi, M., Iwata, S., Kato, H., Ago, H., Yamamoto, M. and Nakatsu, T.:
  "An isomorphous replacement method for efficient de novo phasing for serial femtosecond crystallography."
  Scientific Reports 5, 14017 (2015)
• 9. Suga, M., Akita, F., Hirata, K., Ueno, G., Murakami, H., Nakajima, Y., Shimizu, T., Yamashita, K., Yamamoto, M., Ago, H., and Shen J.R.:
  "Native structure of photosystem II at 1.95A resolution viewed by femtosecond X-ray pulses"
  Nature 517, 99-103 (2015).
• 10. Hirata, K., Shinzawa-Itoh, K., Yano, N., Takemura, S., Kato, K., Hatanaka, M., Muramoto, K., Kawahara, T., Tsukihara, T., Yamashita, E., Tono, K., Ueno, G., Hikima, T., Murakami, H., Inubushi, Y., Yabashi, M., Ishikawa, T., Yamamoto, M., Ogura, T., Sugimoto, H., Shen, J. R., ^*Yoshikawa, S. and Ago, H.:
  "Determination of damage-free crystal structure of an X-ray-sensitive protein using an XFEL"
  Nature Methods 11, 734-746 (2014)

Recent Research Results

• 

  Feb. 9, 2018
  A light touch for enzyme analysis

• 

  Dec. 15, 2017
  How bacteria avoid poisoning themselves

• 

  Sep. 22, 2017
  Watching enzymes inhale

• 

  Feb. 6, 2015
  Shining a gentle light on photosynthesis

• 

  Jul. 18, 2014
  X-ray studies without the damage

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