研究概要

主要論文

「*」は、理研外のみでの成果です。

• 1. Huang, T.-Y., Lemke, S., Wang, Y.-C.:
  "Morphogenetic evolution with physical influences"
  Seminars in Cell & Developmental Biology (2026)
• 2. Dey, B., Kaul, V., Kale, G., et al.
  "Divergent evolutionary strategies pre-empt tissue collision in gastrulation."
  Nature 646(8085), 637-646 (2025)
• 3. Thukral, S., Dey, B., Wang, Y.-C.:
  "Integrating tissue and cytoplasmic rigidity transitions during morphogenesis."
  Development, Growth & Differentiation 67(7), 378-394 (2025)
• 4. Gomez, J. M., Nolte, H., Vogelsang, E., et al.
  "Differential regulation of the proteome and phosphoproteome along the dorso-ventral axis of the early Drosophila embryo."
  eLife 13, e99263 (2024)
• 5. Wen, F.-L., Kwan, C.W., Wang, Y.-C., Shibata, T.:
  "Autonomous epithelial folding induced by an intracellular mechano-polarity feedback loop."
  PLOS Computational Biology 17(12), e1009614 (2021)
• 6. Eritano, A. S., Bromley, C. L., Bolea, Albero, A., et al.
  "Tissue-Scale Mechanical Coupling Reduces Morphogenetic Noise to Ensure Precision during Epithelial Folding."
  Developmental cell 53(2), 212-228 (2020)
• 7. Takeda, M., Sami, M. M., Wang, Y.-C.:
  "A homeostatic apical microtubule network shortens cells for epithelial folding via a basal polarity shift."
  Nature Cell Biology 20, 36-45. (2018)
• 8. Wen, F.-L., Wang, Y.-C., and Shibata, T.:
  "Epithelial folding driven by apical or basal-lateral modulation: geometric features, mechanical inference, and boundary effects."
  Biophys J 112.2683-95 (2017)
• 9. *Wang, Y.-C., Khan, Z., Kaschube, M., and Wieschaus, E. F.:
  "Differential positioning of adherens junctions is associated with initiation of epithelial folding."
  Nature 484.390-3 (2012)
• 10. *Wang, Y.-C., and Ferguson, E. L.
  "Spatial bistability of Dpp-receptor interactions during Drosophila dorsal-ventral patterning."
  Nature 434.229-34 (2005)

研究成果（プレスリリース）

• 

  2025年9月17日
  動物の形づくりに潜む力学的リスク

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