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脳神経科学研究センター グリア-神経回路動態研究チーム

チームリーダー 長井 淳(Ph.D.)


長井 淳(Ph.D.)



  • 総合生物


  • 複合領域
  • 生物学
  • 神経科学(神経生理学・神経科学一般、神経化学・神経薬理学)
  • 動物生理・行動
  • 分子生物学


  • 適応行動
  • 認知と情動
  • グリア細胞
  • 細胞生理学
  • 遺伝学



  • 1. *(*co-first authors) *Yu, X., *Nagai, J., Khakh, B.S.:
    "Improved tools to study astrocytes."
    Nature Reviews Neuroscience 21,121-138. (2020).
  • 2. *Nagai, J., Rajbhandari, A.K., Gangwani, M.R., Hachisuka, A., Coppola, G., Masmanidis, S.C., Fanselow, M.S., Khakh, B.S.:
    "Hyperactivity with disrupted attention induced by activation of an astrocyte synaptogenic cue."
    Cell 177(5), 1280-92. (2019).
  • 3. *Lobas, M., Tao, R., Nagai, J., Kronschlager, M.T., Borden, P., Marvin, J.S., Looger, L.L., Khakh, B.S.:
    "A genetically encoded single-wavelength sensor for imaging cytosolic and cell surface ATP."
    Nature Communications, 10, 711. (2019)
  • 4. *Yu, X., Taylor, A.M.W., Nagai, J., Golshani, P., Evans, C.J., Khakh, B.S.:
    "Reducing astrocyte calcium signaling in vivo alters striatal microcircuits and causes repetitive behavior."
    Neuron, 99(6), 1170-87. (2018).
  • 5. *Nagai, J., Baba, R., Ohshima, T.:
    "CRMPs function in neurons and glial cells: a potential therapeutic target for neurodegenerative disease and CNS injury."
    Molecular Neurobiology, 54(6), 4243-42. (2017)
  • 6. *Nagai, J., Takaya, R., Piao, W., Goshima, Y., Ohshima, T.:
    "Deletion of Crmp4 attenuates CSPG-induced inhibition of axonal growth and induces nociceptive recovery after spinal cord injury."
    Molecular Cellular Neuroscience, 17, 74:42-48. (2016)
  • 7. *Nagai, J., Owada, K., Kitamura, Y., Goshima, Y., Ohshima, T.:
    "Inhibition of CRMP2 phosphorylation repairs CNS by regulating neurotrophic and inhibitory responses."
    Experimental Neurology, 277, 283-95. (2016)
  • 8. *Nagai, J., Kitamura, Y., Owada, K., Yamashita, N., Takei, K., Goshima, Y., Ohshima, T.:
    "Crmp4 deletion promotes recovery from spinal cord injury by neuroprotection and limited scar formation."
    Scientific Reports, 5, 8269. (2015)
  • 9. *Nagai, J., Goshima, Y., Ohshima, T.:
    "CRMP4 mediates MAG-induced inhibition of axonal outgrowth and protection against Vincristine-induced axonal degeneration."
    Neuroscience Letters, 519, 56-61. (2012)



長井 淳


募集職種 応募締切
研究員募集(W20035) ポストが決まり次第
テクニカルスタッフ募集(W20036) ポストが決まり次第


〒351-0198 埼玉県和光市広沢2番1号
Email: jun.nagai [at] riken.jp