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脳神経科学研究センター グリア-神経回路動態研究チーム

チームリーダー 長井 淳(Ph.D.)


長井 淳(Ph.D.)



  • 総合生物


  • 複合領域
  • 生物学
  • 神経科学(神経生理学・神経科学一般、神経化学・神経薬理学)
  • 動物生理・行動
  • 分子生物学


  • 適応行動
  • 認知と情動
  • グリア細胞
  • 細胞生理学
  • 遺伝学



  • 1. Nagai, J., Bellafard, A., Qu, Z., Yu, X., Ollivier, M., Gangwani, M.R., Diaz-Castro, B., Coppola, G., Schumacher, S.M., Golshani, P., Gradinaru, V., Khakh, B.S.
    "Specific and behaviourally consequential astrocyte Gq GPCR signaling attenuation in vivo with iβARK."
    Neuron in press. (2021).
  • 2. *1Wang, W., 1Schuette, P.J., Nagai, J., Tobias, B.C., Cuccovia V Reis, F.M., Ji, S., de Lima, M.A.X., La-Vu, M.Q., Maesta-Pereira, S., Chakerian, M., Leonard, S.J., Lin, L., Severino, A.L., Cahill, C.M., Canteras, N.S., Khakh, B.S., Kao, J.C., Adhikari, A. (1co-first authors)
    "Coordination of escape and spatial navigation circuits orchestrates versatile flight from threats."
    Neuron 109(11):1848-1860. (2021).
  • 3. 1Nagai, J., 1Yu, X., Papouin, T., Cheong, E., Freeman, M.R., Monk, K.R., Hastings, M.H., Haydon, P.G., Rowitch, D., Shaham, S., Khakh, B.S. (1co-first authors)
    "Behaviorally consequential astrocytic regulation of neural circuits."
    Neuron 109(4):576-596. (2021).
  • 4. *1Yu, X., 1Nagai, J., Marti, M., Coppola, G., Babu, M. M., Khakh, B.S.
    "Context-specificastrocyte molecular responses are phenotypically exploitable."
    Neuron 108(6):1146-1162. (2020). (1co-first authors)
  • 5. *1Yu, X., 1Nagai, J., Khakh, B.S. (1co-first authors)
    "Improved tools to study astrocytes."
    Nature Reviews Neuroscience 21,121-138. (2020).
  • 6. *Nagai, J., Rajbhandari, A.K., Gangwani, M.R., Hachisuka, A., Coppola, G., Masmanidis, S.C., Fanselow, M.S., Khakh, B.S.
    "Hyperactivity with disrupted attention induced by activation of an astrocyte synaptogenic cue."
    Cell 177(5), 1280-92. (2019).
  • 7. *Lobas, M., Tao, R., Nagai, J., Kronschlager, M.T., Borden, P., Marvin, J.S., Looger, L.L., Khakh, B.S.
    "A genetically encoded single-wavelength sensor for imaging cytosolic and cell surface ATP."
    Nature Communications, 10, 711. (2019)
  • 8. *Yu, X., Taylor, A.M.W., Nagai, J., Golshani, P., Evans, C.J., Khakh, B.S.
    "Reducing astrocyte calcium signaling in vivo alters striatal microcircuits and causes repetitive behavior."
    Neuron, 99(6), 1170-87. (2018).
  • 9. *Nagai, J., Baba, R., Ohshima, T.
    "CRMPs function in neurons and glial cells: a potential therapeutic target for neurodegenerative disease and CNS injury."
    Molecular Neurobiology, 54(6), 4243-42. (2017)
  • 10. *Nagai, J., Owada, K., Kitamura, Y., Goshima, Y., Ohshima, T.
    "Inhibition of CRMP2 phosphorylation repairs CNS by regulating neurotrophic and inhibitory responses."
    Experimental Neurology, 277, 283-95. (2016)




長井 淳


募集職種 応募締切
研究パートタイマー募集(W22239) ポストが決まり次第


〒351-0198 埼玉県和光市広沢2番1号
Tel: 048-467-6896
Fax: 048-467-6899
Email: jun.nagai [at] riken.jp