研究概要

主要論文

• 1. Carrillo, M., Pandey, S., Sanchez1, J., Noda1, M., Poudyal, I., Aldama, L., Malla, T. N., Claesson, E., Wahlgren, W. Y., Feliz, D., Šrajer, V., Maj, M., Castillon, L., Iwata, S., Nango, E., Tanaka, R., Tanaka, T., Luo, F., Tono, K., Owada, S., Westenhoff, S., Stojković, E. A., Schmidt, M.:
  "High-resolution Crystal Structures of Transient Intermediates in the Phytochrome Photocycle."
  Structure 29, 743-754 (2021)
• 2. Oda, K., Nomura, T., Nakane, T., Yamashita, K., Inoue, K., Ito, S., Vierock, J., Hirata, K., Maturana, A. D., Katayama, K., Ikuta, T., Ishigami, I., Izume, T., Umeda, R., Eguma, R., Oishi, S., Kasuya, G., Kato, T., Kusakizako, T., Shihoya, W., Shimada, H., Takatsuji, T., Takemoto, M., Taniguchi, R., Tomita, A., Nakamura, R., Fukuda, M., Miyauchi, H., Lee, Y., Nango, E., Tanaka, R., Tanaka, T., Sugahara, M., Kimura, T., Shimamura, T., Fujiwara, T., Yamanaka, Y., Owada, S., Joti, Y., Tono, K., Ishitani, R., Hayashi, S., Kandori, H., Hegemann, P., Iwata, S., Kubo, M., Nishizawa, T. & Nureki, O.:
  "Time-Resolved Serial Femtosecond Crystallography Reveals Early Structural Changes in Channelrhodopsin."
  ELife 10, 62389 (2021)
• 3. Claesson, E., Wahlgren, W. Y., Takala, H., Pandey, S., Castillon, L., Kuznetsova, V., Henry, L., Panman, M., Carrillo, M., Kubel, J., Nanekar, R., Isaksson, L., Nimmrich, A., Cellini, A., Morozov, D., Maj, M., Kurttila, M., Bosman, R., Nango, E., Tanaka, R., Tanaka, T., Fangjia, L., Iwata, S., Owada, S., Moffat, K., Groenhof, G., Stojkovic, E. A., Ihalainen, J. A., Schmidt, M. & Westenhoff, S.:
  "The primary structural photoresponse of phytochrome proteins captured by a femtosecond X-ray laser"
  Elife 9, 53514 (2020)
• 4. Wickstrand, C., Katona, G., Nakane, T., Nogly, P., Standfuss, J., Nango, E. & Neutze, R.:
  "A tool for visualizing protein motions in time-resolved crystallography."
  Struct Dyn 7, 024701 (2020)
• 5. Nango, E.^*, Kubo, M.^*, Tono, K., Iwata, S.:
  "Pump-Probe Time-Resolved Serial Femtosecond Crystallography at SACLA: Current Status and Data Collection Strategies."
  Appl. Sci. 9(24), 5505 (2019)
• 6. Shimazua, Y., Tono, K.^*, Tanaka, T., Yamanaka, Y., Nakane, T., Mori, C., Kimura, T. K., Fujiwara, T., Sugahara, M., Tanaka, R., Doak, R. B., Shimamura, T., Iwata, S., Nango, E.^* and Yabashi, M.:
  "High-viscosity sample injection device for serial femtosecond crystallography at atmospheric pressure."
  J. Appl. Cryst. 52, 1280–1288 (2019)
• 7. Nogly, P., Weinert, T., James, D., Carbajo, S., Ozerov, D., Furrer, A., Gashi, D., Borin, V., Skopintsev, P., Jaeger, K., Nass, K., Båth, P., Bosman, R., Koglin, J., Seaberg, M., Lane, T., Kekilli, D., Brünle, S., Tanaka, T., Wu, W., Milne, C., White, T., Barty, A., Weierstall, U., Panneels, V., Nango, E., Iwata, S., Hunter, M., Schapiro, I., Schertler, G., Neutze, R., and Standfuss, J.:
  "Retinal isomerization in bacteriorhodopsin captured by a femtosecond x-ray laser."
  Science 261, 145-152 (2018)
• 8. Kubo, M., Nango, E.^*, Tono, K.^*, Kimura, T., Owada, S., Song, C., Mafuné, F., Miyajima, K., Takeda, Y., Kohno, J. Y., Miyauchi, N., Nakane, T., Tanaka, T., Nomura, T., Davidsson, J., Tanaka, R., Murata, M., Kameshima, T., Hatsui, T., Joti, Y., Neutze, R., Yabashi, M. and Iwata, S.:
  "Nanosecond pump-probe device for time-resolved serial femtosecond crystallography developed at SACLA."
  J. Synchrotron Radiat. 24, 1086-1091 (2017)
• 9. Suga, M., Akita, F., Sugahara, M., Kubo, M., Nakajima, Y., Nakane, T., Yamashita, K., Umena, Y., Nakabayashi, M., Yamane, T., Nakano, T., Suzuki, M., Masuda, T., Inoue, S., Kimura, T., Nomura, T., Yonekura, S., Yu, L. J., Sakamoto, T., Motomura, T., Chen, J. H., Kato, Y., Noguchi, T., Tono, K., Joti, Y., Kameshima, T., Hatsui, T., Nango, E., Tanaka, R., Naitow, H., Matsuura, Y., Yamashita, A., Yamamoto, M., Nureki, O., Yabashi, M., Ishikawa, T., Iwata, S. and Shen, J. R.:
  "Light-induced structural changes and the site of O=O bond formation in PSII caught by XFEL."
  Nature 543, 131–135 (2017)
• 10. Nango, E., Royant, A., Kubo, M., Nakane, T., Wickstrand, C., Kimura, T., Tanaka, T., Tono, K., Song, C., Tanaka, R., Arima, T., Yamashita, A., Kobayashi, J., Hosaka, T., Mizohata, E., Nogly, P., Sugahara, M., Nam, D., Nomura, T., Shimamura, T., Im, D., Fujiwara, T., Yamanaka, Y., Jeon, B., Nishizawa, T., Oda, K., Fukuda, M., Andersson, R., Bath, P., Dods, R., Davidsson, J., Matsuoka, S., Kawatake, S., Murata, M., Nureki, O., Owada, S., Kameshima, T., Hatsui, T., Joti, Y., Schertler, G., Yabashi, M., Bondar, A. N., Standfuss, J., Neutze, R. and Iwata, S.:
  "A three-dimensional movie of structural changes in bacteriorhodopsin."
  Science 354, 1552-1557 (2016)

研究成果（プレスリリース）

• 

  2024年7月8日
  タンパク質結晶に分子を閉じ込め反応過程を可視化

• 

  2023年9月19日
  温度による酵素の構造変化を分子動画撮影

• 

  2023年7月21日
  光スイッチ型蛍光タンパク質の反応を可視化

• 

  2023年3月23日
  視覚に関わるタンパク質の超高速分子動画

関連リンク

メンバーリスト

お問い合わせ先